Details of Metabolite (Meta)

General Information of Metabolite (ID: MT094)
  Meta Name
Arachidonic acid
  Unify Name
Arachidonic acid
  Synonym    Click to Show/Hide the Detailed Synonyms of This Metabolite
(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid;(5Z,8Z,11Z,14Z)-Icosatetraenoic acid;AA;all-cis-5,8,11,14-Eicosatetraenoic acid;ARA;Arachidonate;Arachidonsaeure;cis-5,8,11,14-Eicosatetraenoic acid;cis-Delta(5,8,11,14)-Eicosatetraenoic acid;(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoate;(5Z,8Z,11Z,14Z)-Icosatetraenoate;all-cis-5,8,11,14-Eicosatetraenoate;cis-5,8,11,14-Eicosatetraenoate;cis-delta(5,8,11,14)-Eicosatetraenoate;cis-delta(5,8,11,14)-eicosatetraenoate;cis-delta(5,8,11,14)-eicosatetraenoic acid;(all-Z)-5,8,11,14-Eicosatetraenoate;(all-Z)-5,8,11,14-Eicosatetraenoic acid;5,8,11,14-all-cis-Eicosatetraenoate;5,8,11,14-all-cis-Eicosatetraenoic acid;5,8,11,14-Eicosatetraenoate;5,8,11,14-Eicosatetraenoic acid;5-cis,8-cis,11-cis,14-cis-Eicosatetraenoate;5-cis,8-cis,11-cis,14-cis-Eicosatetraenoic acid;5Z,8Z,11Z,14Z-Eicosatetraenoate;5Z,8Z,11Z,14Z-Eicosatetraenoic acid;cis-D5,8,11,14-Eicosatetraenoate;cis-D5,8,11,14-Eicosatetraenoic acid;Immunocytophyte;Arachidonate, sodium;Arachidonic acid, (all-Z)-isomer, 3H-labeled;Arachidonic acid, ammonium salt, (all-Z)-isomer;Arachidonic acid, cerium salt, (all-Z)-isomer;Arachidonic acid, sodium salt;Arachidonic acid, sodium salt, (all-Z)-isomer;Vitamin F;Arachidonic acid, cesium salt, (all-Z)-isomer;Arachidonic acid, lithium salt, (all-Z)-isomer;Arachidonic acid, potassium salt, (all-Z)-isomer;Sodium arachidonate;Arachidonic acid, (all-Z)-isomer, 1-(14)C-labeled;Arachidonic acid, zinc salt, (all-Z)-isomer;FA(20:4(5Z,8Z,11Z,14Z))
  Molecule Type
Polyunsaturated fatty acid (PUFAs)
  Formula
C20H31O2
  Inchi Key
YZXBAPSDXZZRGB-DOFZRALJSA-M
  Description    Click to Show/Hide the Detailed Description of This Metabolite
Human Metabolome Database (HMDB): Arachidonic acid is a polyunsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid. Arachidonic acid mediates inflammation and the functioning of several organs and systems either directly or upon its conversion into eicosanoids. Arachidonic acid in cell membrane phospholipids is the substrate for the synthesis of a range of biologically active compounds (eicosanoids) including prostaglandins, thromboxanes, and leukotrienes. These compounds can act as mediators in their own right and can also act as regulators of other processes, such as platelet aggregation, blood clotting, smooth muscle contraction, leukocyte chemotaxis, inflammatory cytokine production, and immune function. Arachidonic acid can be metabolized by cytochrome p450 (CYP450) enzymes to 5,6-, 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids (EETs), their corresponding dihydroxyeicosa-trienoic acids (DHETs), and 20-hydroxyeicosatetraenoic acid (20-HETE). The production of kidney CYP450 arachidonic acid metabolites is altered in diabetes, pregnancy, hepatorenal syndrome, and in various models of hypertension, and it is likely that changes in this system contribute to the abnormalities in renal function that are associated with many of these conditions. Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (PMID: 12736897, 12736897, 12700820, 12570747, 12432908).
  External Links   HMDB ID   HMDB0001043
  VMH ID   arachd
  KEGG ID   C00219
  Metlin ID   193

The epigenetic modification information of this metabolite
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA Hypermethylation ABCF1 EM Info THP-1 cells cg00678158 . [1], [2]
DNA Hypermethylation ABI1 EM Info THP-1 cells cg18825419 . [1], [3]
DNA Hypermethylation ACAT2 EM Info THP-1 monocytes cg25736982 . [4], [5]
DNA Hypermethylation ACOT7 EM Info THP-1 monocytes cg04309375 . [4], [5]
DNA Hypermethylation ACOX3 EM Info THP-1 monocytes cg08206079 . [4], [5]
DNA Hypermethylation ADAMTS3 EM Info THP-1 monocytes cg01664241 . [4], [5]
DNA Hypermethylation ADAMTS3 EM Info THP-1 monocytes cg07974833 . [4], [5]
DNA Hypermethylation ADAMTS9 EM Info THP-1 monocytes cg00508543 . [4], [5]
DNA Hypermethylation ADARB1 EM Info THP-1 cells cg05516004 . [1], [3]
DNA Hypermethylation ADARB2 EM Info THP-1 monocytes cg05630272 . [4], [5]
DNA Hypermethylation ADARB2 EM Info THP-1 monocytes cg13911959 . [4], [5]
DNA Hypermethylation ADCY1 EM Info THP-1 monocytes cg14919164 . [4], [5]
DNA Hypermethylation ADCY7 EM Info THP-1 monocytes cg16548911 . [4], [5]
DNA Hypermethylation ADSL EM Info THP-1 monocytes cg27304757 . [4], [5]
DNA Hypermethylation AGL EM Info THP-1 monocytes cg18377446 . [4], [5]
DNA Hypermethylation AGRN EM Info THP-1 cells cg11853970 . [4]
DNA Hypermethylation AHCYL2 EM Info THP-1 monocytes cg25969460 . [4], [5]
DNA Hypermethylation AHNAK EM Info THP-1 monocytes cg16509239 . [4], [5]
DNA Hypermethylation AK3L1 EM Info THP-1 cells cg00009916 . [4]
DNA Hypermethylation ALG14 EM Info THP-1 monocytes cg23653667 . [4], [5]
DNA Hypermethylation APH1B EM Info THP-1 monocytes cg21888989 . [4], [5]
DNA Hypermethylation ARHGAP11B EM Info THP-1 monocytes cg04422277 . [4], [5]
DNA Hypermethylation ARHGEF18 EM Info THP-1 monocytes cg01797160 . [4], [5]
DNA Hypermethylation ARL2 EM Info THP-1 cells cg10160630 . [4], [6]
DNA Hypermethylation ARRDC2 EM Info THP-1 monocytes cg05845141 . [7], [2]
DNA Hypermethylation ASB1 EM Info THP-1 monocytes cg19072128 . [4], [5]
DNA Hypermethylation ATP11A EM Info THP-1 cells cg08557929 . [4]
DNA Hypermethylation ATP2B2 EM Info THP-1 monocytes cg15314542 . [4], [5]
DNA Hypermethylation ATP6V0D2 EM Info THP-1 monocytes cg01248426 . [4], [5]
DNA Hypermethylation ATR EM Info THP-1 monocytes cg12825470 . [4], [5]
DNA Hypermethylation ATXN7L1 EM Info THP-1 monocytes cg15910895 . [8], [9]
DNA Hypermethylation ATXN7L1 EM Info THP-1 monocytes cg07714289 . [10], [4]
DNA Hypermethylation B3GAT1 EM Info THP-1 cells cg16635108 . [11], [2]
DNA Hypermethylation BAALC EM Info THP-1 monocytes cg02389252 . [4], [5]
DNA Hypermethylation BACE2 EM Info THP-1 monocytes cg04954795 . [4], [5]
DNA Hypermethylation BARX2 EM Info THP-1 monocytes cg15571705 . [4], [5]
DNA Hypermethylation BAT1 EM Info THP-1 cells cg21545988 . [12], [2]
DNA Hypermethylation BCAS3 EM Info THP-1 monocytes cg22435132 . [4], [5]
DNA Hypermethylation BCAT2 EM Info THP-1 cells cg23455517 . [4], [13]
DNA Hypermethylation BCL2L1 EM Info THP-1 monocytes cg25291404 . [4], [5]
DNA Hypermethylation BCOR EM Info THP-1 monocytes cg18765710 . [4], [5]
DNA Hypermethylation BEND3 EM Info THP-1 monocytes cg17978996 . [4], [14]
DNA Hypermethylation BMPR1A EM Info THP-1 monocytes cg24211476 . [4], [14]
DNA Hypermethylation BRDT EM Info THP-1 monocytes cg13299824 . [4], [14]
DNA Hypermethylation BTBD2 EM Info THP-1 cells cg15773755 . [4], [13]
DNA Hypermethylation C10orf47 EM Info THP-1 cells cg23532197 . [4], [13]
DNA Hypermethylation C11orf64 EM Info THP-1 cells cg10942775 . [15], [16]
DNA Hypermethylation C16orf58 EM Info THP-1 cells cg09231536 . [15], [16]
DNA Hypermethylation C17orf44 EM Info THP-1 cells cg26910280 . [17], [16]
DNA Hypermethylation C17orf48 EM Info THP-1 cells cg03592161 . [18], [19]
DNA Hypermethylation C19orf29 EM Info THP-1 cells cg09268313 . [7], [3]
DNA Hypermethylation C1orf86 EM Info THP-1 monocytes cg26227225 . [4], [14]
DNA Hypermethylation C1QTNF6 EM Info THP-1 cells cg11793380 . [7], [3]
DNA Hypermethylation C20orf107 EM Info THP-1 cells cg00272992 . [17], [16]
DNA Hypermethylation C20orf94 EM Info THP-1 monocytes ch.20.230983F . [7], [2]
DNA Hypermethylation C22orf25 EM Info THP-1 monocytes cg13570637 . [4]
DNA Hypermethylation C2orf51 EM Info THP-1 monocytes cg09259581 . [4]
DNA Hypermethylation C2orf55 EM Info THP-1 monocytes cg19055178 . [4]
DNA Hypermethylation C3orf26 EM Info THP-1 monocytes cg15963552 . [4]
DNA Hypermethylation C6orf127 EM Info THP-1 monocytes cg08974492 . [4]
DNA Hypermethylation C6orf15 EM Info THP-1 monocytes cg16150435 . [4]
DNA Hypermethylation C7orf44 EM Info THP-1 monocytes cg15556709 . [4], [6]
DNA Hypermethylation C9orf163 EM Info THP-1 monocytes cg14512731 . [20], [19]
DNA Hypermethylation C9orf47 EM Info THP-1 monocytes cg13575422 . [4], [5]
DNA Hypermethylation CACNA1H EM Info THP-1 monocytes cg03271813 . [15], [21]
DNA Hypermethylation CADM1 EM Info THP-1 monocytes cg02788102 . [4], [5]
DNA Hypermethylation CADPS EM Info THP-1 monocytes cg02041899 . [4], [5]
DNA Hypermethylation CAMKK2 EM Info THP-1 monocytes cg17541002 . [15], [21]
DNA Hypermethylation CAMSAP1 EM Info THP-1 monocytes cg07166653 . [4], [5]
DNA Hypermethylation CAMTA1 EM Info THP-1 monocytes cg08941669 . [4], [5]
DNA Hypermethylation CARD11 EM Info THP-1 monocytes cg24345260 . [8], [9]
DNA Hypermethylation CARS2 EM Info THP-1 monocytes cg26658796 . [1], [9]
DNA Hypermethylation CBLC EM Info THP-1 monocytes cg23031103 . [17], [21]
DNA Hypermethylation CCDC88C EM Info THP-1 monocytes cg05238553 . [4], [22]
DNA Hypermethylation CCDC88C EM Info THP-1 monocytes cg04043826 . [8], [9]
DNA Hypermethylation CCDC93 EM Info THP-1 monocytes cg24475517 . [4], [5]
DNA Hypermethylation CCDC97 EM Info THP-1 monocytes cg08398371 . [17], [21]
DNA Hypermethylation CCNB1IP1 EM Info THP-1 monocytes cg19010223 . [17], [21]
DNA Hypermethylation CDH23 EM Info THP-1 monocytes cg12830671 . [4], [5]
DNA Hypermethylation CEP164 EM Info THP-1 monocytes cg21655201 . [4], [5]
DNA Hypermethylation CGB8 EM Info THP-1 monocytes cg12515942 . [17], [21]
DNA Hypermethylation CHCHD3 EM Info THP-1 monocytes cg00446758 . [4], [5]
DNA Hypermethylation CHD5 EM Info THP-1 monocytes cg17479763 . [17], [21]
DNA Hypermethylation CHMP1A EM Info THP-1 monocytes cg05441039 . [4], [23]
DNA Hypermethylation CIT EM Info THP-1 monocytes cg24889207 . [4], [5]
DNA Hypermethylation CLEC4C EM Info THP-1 monocytes cg01120761 . [4], [23]
DNA Hypermethylation CLIP2 EM Info THP-1 monocytes cg01338634 . [4], [23]
DNA Hypermethylation CLIP2 EM Info THP-1 monocytes cg13327407 . [4], [23]
DNA Hypermethylation CLK4 EM Info THP-1 monocytes cg03127127 . [1], [4]
DNA Hypermethylation CMC1 EM Info THP-1 monocytes cg03144753 . [4], [5]
DNA Hypermethylation CNKSR2 EM Info THP-1 monocytes cg23617392 . [4], [5]
DNA Hypermethylation COL4A2 EM Info THP-1 monocytes cg23119039 . [4], [23]
DNA Hypermethylation CPSF6 EM Info THP-1 monocytes cg03559836 . [4], [5]
DNA Hypermethylation CRADD EM Info THP-1 monocytes cg23535137 . [4], [5]
DNA Hypermethylation CSN1S1 EM Info THP-1 monocytes cg09096383 . [4], [23]
DNA Hypermethylation CSRP2BP EM Info THP-1 monocytes cg11564623 . [4], [5]
DNA Hypermethylation CTSA EM Info THP-1 monocytes cg19067730 . [1], [4]
DNA Hypermethylation CUX1 EM Info THP-1 monocytes cg18275467 . [4], [5]
DNA Hypermethylation CXXC4 EM Info THP-1 monocytes cg18642003 . [4], [5]
DNA Hypermethylation CYFIP2 EM Info THP-1 monocytes cg08224785 . [4], [5]
DNA Hypermethylation CYP26C1 EM Info THP-1 monocytes cg05219493 . [4], [5]
DNA Hypermethylation CYP2C9 EM Info THP-1 monocytes cg24140586 . [4], [5]
DNA Hypermethylation DAZL EM Info THP-1 monocytes cg27248643 . [4], [23]
DNA Hypermethylation DDC EM Info THP-1 monocytes cg05346287 . [4], [23]
DNA Hypermethylation DDX21 EM Info THP-1 monocytes cg02393449 . [4], [23]
DNA Hypermethylation DEFB108B EM Info THP-1 monocytes cg19810628 . [4], [23]
DNA Hypermethylation DEPDC1B EM Info THP-1 monocytes cg17504997 . [4], [23]
DNA Hypermethylation DHRS3 EM Info THP-1 monocytes cg10523319 . [4], [5]
DNA Hypermethylation DHX16 EM Info THP-1 monocytes cg01538969 . [4], [23]
DNA Hypermethylation DIP2C EM Info THP-1 monocytes cg05661869 . [4], [5]
DNA Hypermethylation DIP2C EM Info THP-1 monocytes cg20472384 . [4], [5]
DNA Hypermethylation DLG2 EM Info THP-1 monocytes cg09411876 . [4], [5]
DNA Hypermethylation DNAH3 EM Info THP-1 monocytes cg07079231 . [4], [5]
DNA Methylation DNMT EM Info . . . [1], [4]
DNA Hypermethylation DOK7 EM Info THP-1 monocytes cg05620676 . [4], [23]
DNA Hypermethylation DOK7 EM Info THP-1 monocytes cg21333208 . [4], [23]
DNA Hypermethylation DPP6 EM Info THP-1 monocytes cg05521981 . [4], [5]
DNA Hypermethylation DSCAML1 EM Info THP-1 monocytes cg06468072 . [4], [5]
DNA Hypermethylation DSE EM Info THP-1 monocytes cg24407607 . [4], [5]
DNA Hypermethylation DYRK3 EM Info THP-1 monocytes cg17717238 . [4], [5]
DNA Hypermethylation EDIL3 EM Info THP-1 monocytes cg11559250 . [4], [5]
DNA Hypermethylation ENDOD1 EM Info THP-1 monocytes cg16317734 . [4], [5]
DNA Hypermethylation EP400NL EM Info THP-1 monocytes cg02039634 . [4], [23]
DNA Hypermethylation EPPK1 EM Info THP-1 monocytes cg06668829 . [4], [5]
DNA Hypermethylation ERCC2 EM Info THP-1 monocytes cg03041824 . [4], [5]
DNA Hypermethylation ERG EM Info THP-1 monocytes cg16962191 . [4], [5]
DNA Hypermethylation ERGIC1 EM Info THP-1 monocytes cg18034299 . [4], [5]
DNA Hypermethylation ESR2 EM Info THP-1 monocytes cg11070000 . [4], [5]
DNA Hypermethylation ESRRB EM Info THP-1 monocytes cg18917736 . [4], [5]
DNA Hypermethylation EXOC4 EM Info THP-1 monocytes cg17362299 . [4], [5]
DNA Hypermethylation FADS2 EM Info THP-1 monocytes cg07999042 . [4], [23]
DNA Hypermethylation FAM171A1 EM Info THP-1 monocytes cg12069423 . [4], [5]
DNA Hypermethylation FAM194A EM Info THP-1 monocytes cg03909821 . [4], [5]
DNA Hypermethylation FAM53A EM Info THP-1 monocytes cg14847236 . [4], [5]
DNA Hypermethylation FAM59A EM Info THP-1 monocytes cg18086635 . [24], [4]
DNA Hypermethylation FARP2 EM Info THP-1 monocytes cg00707741 . [4], [5]
DNA Hypermethylation FAS EM Info THP-1 monocytes cg06450397 . [4], [5]
DNA Hypermethylation FAT1 EM Info THP-1 monocytes cg24337359 . [4], [5]
DNA Hypermethylation FBXL13 EM Info THP-1 monocytes cg08832745 . [4], [5]
DNA Hypermethylation FER1L6 EM Info THP-1 monocytes cg00664222 . [4], [5]
DNA Hypermethylation FGFBP1 EM Info THP-1 monocytes cg17091967 . [4], [5]
DNA Hypermethylation FGFR1 EM Info THP-1 monocytes cg12614213 . [4], [5]
DNA Hypermethylation FHIT EM Info THP-1 monocytes cg16986494 . [4], [5]
DNA Hypermethylation FHIT EM Info THP-1 monocytes cg17573813 . [4], [5]
DNA Hypermethylation FLAD1 EM Info THP-1 monocytes cg08260299 . [4], [5]
DNA Hypermethylation FOXO3 EM Info THP-1 monocytes cg05008218 . [4], [5]
DNA Hypermethylation FOXP2 EM Info THP-1 monocytes cg02647628 . [4], [5]
DNA Hypermethylation FST EM Info THP-1 monocytes cg05916662 . [4], [25]
DNA Hypermethylation GAK EM Info THP-1 monocytes cg16475712 . [4], [5]
DNA Hypermethylation GAL3ST3 EM Info THP-1 monocytes cg14780632 . [4], [5]
DNA Hypermethylation GALNTL5 EM Info THP-1 monocytes cg25213550 . [4], [5]
DNA Hypermethylation GAS7 EM Info THP-1 monocytes cg12642651 . [4], [5]
DNA Hypermethylation GJA3 EM Info THP-1 monocytes cg21301341 . [4], [5]
DNA Hypermethylation GJA5 EM Info THP-1 monocytes cg11423701 . [4], [26]
DNA Hypermethylation GLRX3 EM Info THP-1 monocytes cg18986589 . [4], [5]
DNA Hypermethylation GMIP EM Info THP-1 monocytes cg00416475 . [4], [5]
DNA Hypermethylation GOLIM4 EM Info THP-1 monocytes cg15254860 . [4], [5]
DNA Hypermethylation GPC3 EM Info THP-1 monocytes cg14586560 . [4], [5]
DNA Hypermethylation GPD2 EM Info THP-1 monocytes cg15871509 . [4], [5]
DNA Hypermethylation GPR115 EM Info THP-1 monocytes cg20457051 . [4], [5]
DNA Hypermethylation GPR123 EM Info THP-1 monocytes cg20012537 . [4], [5]
DNA Hypermethylation GPR85 EM Info THP-1 monocytes cg01491795 . [4], [5]
DNA Hypermethylation GPRIN3 EM Info THP-1 monocytes cg03265664 . [4], [5]
DNA Hypermethylation GRM3 EM Info THP-1 monocytes cg01449218 . [4], [5]
DNA Hypermethylation GRM4 EM Info THP-1 monocytes cg27428129 . [4], [5]
DNA Hypermethylation GRPEL1 EM Info THP-1 monocytes cg03847636 . [4], [5]
DNA Hypermethylation GSTZ1 EM Info THP-1 monocytes cg15561986 . [4], [5]
DNA Hypermethylation GTF2H4 EM Info THP-1 monocytes cg26935722 . [4], [5]
DNA Hypermethylation HAPLN1 EM Info THP-1 monocytes cg10536076 . [4], [5]
DNA Hypermethylation HDAC4 EM Info THP-1 monocytes cg26686512 . [4], [5]
DNA Hypermethylation HIP1 EM Info THP-1 monocytes cg09346547 . [4], [5]
DNA Hypermethylation HIST3H2A EM Info THP-1 monocytes cg11343017 . [4], [5]
DNA Hypermethylation HIST3H2BB EM Info THP-1 monocytes cg17515024 . [4], [5]
DNA Hypermethylation HLA-A EM Info THP-1 monocytes cg16742075 . [4], [5]
DNA Hypermethylation HLA-DOA EM Info THP-1 monocytes cg18824596 . [4], [5]
DNA Hypermethylation HLA-H EM Info THP-1 monocytes cg20114890 . [4], [5]
DNA Hypermethylation HOXC9 EM Info THP-1 monocytes cg03215137 . [4], [5]
DNA Hypermethylation HSPG2 EM Info THP-1 monocytes cg11419235 . [4], [5]
DNA Hypermethylation IDH3B EM Info THP-1 monocytes cg23469025 . [4], [5]
DNA Hypermethylation IGFL4 EM Info THP-1 monocytes cg25574111 . [4], [27]
DNA Hypermethylation IGJ EM Info THP-1 monocytes cg03968222 . [4], [5]
DNA Hypermethylation IL1RAPL2 EM Info THP-1 monocytes cg22522299 . [4], [5]
DNA Hypermethylation INPP1 EM Info THP-1 monocytes cg25110245 . [4], [5]
DNA Hypermethylation INPP4B EM Info THP-1 monocytes cg10380019 . [4], [5]
DNA Hypermethylation INPP5A EM Info THP-1 monocytes cg20210689 . [4], [5]
DNA Hypermethylation INTS1 EM Info THP-1 monocytes cg13761594 . [4], [5]
DNA Hypermethylation IPMK EM Info THP-1 monocytes cg10256686 . [4], [5]
DNA Hypermethylation IQCE EM Info THP-1 monocytes cg16313758 . [4], [5]
DNA Hypermethylation IQCE EM Info THP-1 monocytes cg16460498 . [4], [5]
DNA Hypermethylation ISLR EM Info THP-1 monocytes cg15480336 . [4], [5]
DNA Hypermethylation ISOC1 EM Info THP-1 monocytes cg06928924 . [4], [5]
DNA Hypermethylation ITGB1BP3 EM Info THP-1 monocytes cg11960711 . [4], [5]
DNA Hypermethylation JAK1 EM Info THP-1 monocytes cg02755455 . [4], [5]
DNA Hypermethylation JPH1 EM Info THP-1 monocytes cg05350802 . [4], [5]
DNA Hypermethylation JSRP1 EM Info THP-1 monocytes cg11449372 . [4], [5]
DNA Hypermethylation KBTBD11 EM Info THP-1 monocytes cg06316133 . [4], [5]
DNA Hypermethylation KCND2 EM Info THP-1 monocytes cg24565369 . [4], [5]
DNA Hypermethylation KCNK3 EM Info THP-1 monocytes cg02793733 . [4], [5]
DNA Hypermethylation KCNMA1 EM Info THP-1 monocytes cg15754112 . [4], [5]
DNA Hypermethylation KCNQ1 EM Info THP-1 monocytes cg04008557 . [4], [5]
DNA Hypermethylation KCNQ2 EM Info THP-1 monocytes cg09117405 . [4], [5]
DNA Hypermethylation KCNS1 EM Info THP-1 monocytes cg24283270 . [4], [5]
DNA Hypermethylation KIAA0284 EM Info THP-1 monocytes cg05160272 . [4], [5]
DNA Hypermethylation KIAA0284 EM Info THP-1 monocytes cg26985447 . [4], [5]
DNA Hypermethylation KIAA0892 EM Info THP-1 monocytes cg17491846 . [4], [5]
DNA Hypermethylation KIAA1310 EM Info THP-1 monocytes cg07018853 . [4], [5]
DNA Hypermethylation KIAA1430 EM Info THP-1 monocytes cg22096870 . [4], [5]
DNA Hypermethylation KLC3 EM Info THP-1 monocytes cg25481705 . [4], [5]
DNA Hypermethylation KLHDC4 EM Info THP-1 monocytes cg04043336 . [4], [5]
DNA Hypermethylation KLHL29 EM Info THP-1 monocytes cg13774015 . [4], [5]
DNA Hypermethylation KLHL29 EM Info THP-1 monocytes cg15996406 . [4], [5]
DNA Hypermethylation KNCN EM Info THP-1 monocytes cg24663236 . [4], [5]
DNA Hypermethylation KRT2 EM Info THP-1 monocytes cg02699834 . [4], [5]
DNA Hypermethylation LEPREL2 EM Info THP-1 monocytes cg17777408 . [4], [5]
DNA Hypermethylation LGTN EM Info THP-1 monocytes ch.1.4018176R . [4], [5]
DNA Hypermethylation LIPK EM Info THP-1 monocytes cg18783033 . [4], [5]
DNA Hypermethylation LOC100130017 EM Info THP-1 monocytes cg17282466 . [4], [5]
DNA Hypermethylation LOC100288797 EM Info THP-1 monocytes cg27609986 . [4], [5]
DNA Hypermethylation LOC100303728 EM Info THP-1 monocytes cg15913856 . [4], [5]
DNA Hypermethylation LOC440839 EM Info THP-1 monocytes cg27078464 . [4], [5]
DNA Hypermethylation LOC647979 EM Info THP-1 monocytes cg23573114 . [4], [5]
DNA Hypermethylation LOC729991-MEF2B EM Info THP-1 monocytes cg01680573 . [4], [5]
DNA Hypermethylation LOC93622 EM Info THP-1 monocytes cg04672903 . [4], [5]
DNA Hypermethylation LPP EM Info THP-1 monocytes cg04423294 . [4], [5]
DNA Hypermethylation LRCH3 EM Info THP-1 monocytes cg12741295 . [4], [5]
DNA Hypermethylation LRP5 EM Info THP-1 monocytes cg05360160 . [4], [5]
DNA Hypermethylation LRRC23 EM Info THP-1 monocytes cg13003996 . [4], [5]
DNA Hypermethylation LYSMD2 EM Info THP-1 monocytes cg22398093 . [4], [5]
DNA Hypermethylation MAGI1 EM Info THP-1 monocytes cg03845962 . [4], [5]
DNA Hypermethylation MAP1B EM Info THP-1 monocytes cg24661274 . [4], [5]
DNA Hypermethylation MAP7 EM Info THP-1 monocytes cg14119158 . [4], [5]
DNA Hypermethylation MARVELD1 EM Info THP-1 monocytes cg25355803 . [4], [5]
DNA Hypermethylation MBNL2 EM Info THP-1 monocytes cg24341515 . [4], [5]
DNA Hypermethylation MCAT EM Info THP-1 monocytes cg01827908 . [4], [5]
DNA Hypermethylation MCTP2 EM Info THP-1 monocytes cg10658203 . [4], [5]
DNA Hypermethylation ME3 EM Info THP-1 monocytes cg08674281 . [4], [5]
DNA Hypermethylation MEGF6 EM Info THP-1 monocytes cg21156590 . [4], [5]
DNA Hypermethylation MEST EM Info THP-1 monocytes cg09425926 . [4], [5]
DNA Hypermethylation METTL14 EM Info THP-1 monocytes cg24763126 . [4], [5]
DNA Hypermethylation MFSD4 EM Info THP-1 monocytes cg21012061 . [4], [5]
DNA Hypermethylation MGAT1 EM Info THP-1 monocytes cg25332357 . [4], [5]
DNA Hypermethylation MIR183 EM Info THP-1 monocytes cg06242719 . [4], [5]
DNA Hypermethylation MIR487A EM Info THP-1 monocytes cg16438722 . [4], [5]
DNA Hypermethylation MKLN1 EM Info THP-1 monocytes cg04851652 . [4], [5]
DNA Hypermethylation MLH1 EM Info THP-1 monocytes cg04777024 . [4], [5]
DNA Hypermethylation MLL5 EM Info THP-1 monocytes cg20770516 . [4], [5]
DNA Hypermethylation MLLT4 EM Info THP-1 monocytes cg06034664 . [4], [5]
DNA Hypermethylation MMP21 EM Info THP-1 monocytes cg05670995 . [4], [5]
DNA Hypermethylation MRPL30 EM Info THP-1 monocytes cg24654185 . [4], [5]
DNA Hypermethylation MSH4 EM Info THP-1 monocytes cg21438018 . [4], [5]
DNA Hypermethylation MSRB3 EM Info THP-1 monocytes cg09421347 . [4], [5]
DNA Hypermethylation MTMR9L EM Info THP-1 monocytes cg09942999 . [4], [5]
DNA Hypermethylation MXRA5 EM Info THP-1 monocytes cg17410803 . [4], [5]
DNA Hypermethylation MYH15 EM Info THP-1 monocytes cg18743305 . [4], [5]
DNA Hypermethylation NAV2 EM Info THP-1 monocytes cg12361088 . [4], [5]
DNA Hypermethylation NBR1 EM Info THP-1 monocytes cg09019013 . [4], [5]
DNA Hypermethylation NCOR2 EM Info THP-1 monocytes cg20605103 . [4], [5]
DNA Hypermethylation NFU1 EM Info THP-1 monocytes cg11644052 . [4], [5]
DNA Hypermethylation NGF EM Info THP-1 monocytes cg26678187 . [4], [5]
DNA Hypermethylation NLRP11 EM Info THP-1 monocytes cg22747516 . [4], [5]
DNA Hypermethylation NNT EM Info THP-1 monocytes cg09747230 . [4], [5]
DNA Hypermethylation NPL EM Info THP-1 monocytes cg00548060 . [4], [5]
DNA Hypermethylation NPPA EM Info THP-1 monocytes cg20202438 . [4], [5]
DNA Hypermethylation NRG2 EM Info THP-1 monocytes cg11217865 . [4], [5]
DNA Hypermethylation NTN4 EM Info THP-1 monocytes cg16318311 . [4], [5]
DNA Hypermethylation NXN EM Info THP-1 monocytes cg06265760 . [4], [5]
DNA Hypermethylation NXPH1 EM Info THP-1 monocytes cg24529280 . [4], [5]
DNA Hypermethylation OCEL1 EM Info THP-1 monocytes cg19461907 . [4], [5]
DNA Hypermethylation ODZ3 EM Info THP-1 monocytes cg03242448 . [4], [5]
DNA Hypermethylation OPCML EM Info THP-1 monocytes cg05035315 . [4], [5]
DNA Hypermethylation OR5H2 EM Info THP-1 monocytes cg06337592 . [4], [5]
DNA Hypermethylation OR5T2 EM Info THP-1 monocytes cg19724485 . [4], [5]
DNA Hypermethylation OR8B8 EM Info THP-1 monocytes cg03460239 . [4], [5]
DNA Hypermethylation OSTM1 EM Info THP-1 monocytes cg05035406 . [4], [5]
DNA Hypermethylation PABPC4L EM Info THP-1 monocytes cg15867829 . [4], [5]
DNA Hypermethylation PAGE3 EM Info THP-1 monocytes cg17122511 . [4], [5]
DNA Hypermethylation PAQR6 EM Info THP-1 monocytes cg10544251 . [4], [5]
DNA Hypermethylation PCDHA2 EM Info THP-1 monocytes cg21619814 . [4], [5]
DNA Hypermethylation PCDHB5 EM Info THP-1 monocytes cg19568544 . [4], [5]
DNA Hypermethylation PCDP1 EM Info THP-1 monocytes cg09803758 . [4], [5]
DNA Hypermethylation PCGF3 EM Info THP-1 monocytes cg17547928 . [4], [5]
DNA Hypermethylation PDE3A EM Info THP-1 monocytes cg23367478 . [4], [5]
DNA Hypermethylation PDZD4 EM Info THP-1 monocytes cg01529679 . [4], [5]
DNA Hypermethylation PEBP4 EM Info THP-1 monocytes cg22134757 . [4], [5]
DNA Hypermethylation PFKP EM Info THP-1 monocytes cg08811336 . [4], [5]
DNA Hypermethylation PHF12 EM Info THP-1 monocytes cg04164584 . [4], [5]
DNA Hypermethylation PIF1 EM Info THP-1 monocytes cg06238779 . [4], [5]
DNA Hypermethylation PKD1L1 EM Info THP-1 monocytes cg15042302 . [4], [5]
DNA Hypermethylation PKD2 EM Info THP-1 monocytes cg03266576 . [4], [5]
DNA Hypermethylation PLEKHG5 EM Info THP-1 monocytes cg01429933 . [4], [5]
DNA Hypermethylation PLK2 EM Info THP-1 monocytes cg17629870 . [4], [5]
DNA Hypermethylation PNMA1 EM Info THP-1 monocytes cg09119665 . [4], [27]
DNA Hypermethylation PNMA2 EM Info THP-1 monocytes cg24558112 . [4], [5]
DNA Hypermethylation PPA2 EM Info THP-1 monocytes cg25083636 . [4], [5]
DNA Hypermethylation PRDM11 EM Info THP-1 monocytes cg05515072 . [4], [5]
DNA Hypermethylation PRICKLE2 EM Info THP-1 monocytes cg08877148 . [4], [5]
DNA Hypermethylation PRKAG2 EM Info THP-1 monocytes cg05807157 . [4], [5]
DNA Hypermethylation ProSAPiP1 EM Info THP-1 monocytes cg17153082 . [4], [5]
DNA Hypermethylation PRPF4 EM Info THP-1 monocytes cg21174750 . [4], [5]
DNA Hypermethylation PSMB8 EM Info THP-1 monocytes cg24031377 . [4], [5]
DNA Hypermethylation PSMB9 EM Info THP-1 monocytes cg00045690 . [4], [5]
DNA Hypermethylation PTBP1 EM Info THP-1 monocytes cg08918206 . [4], [5]
DNA Hypermethylation PTCH1 EM Info THP-1 monocytes cg01222719 . [4], [5]
DNA Hypermethylation PTF1A EM Info THP-1 monocytes cg24767148 . [4], [5]
DNA Hypermethylation PTGS2 EM Info THP-1 monocytes cg17419623 . [4], [5]
DNA Hypermethylation PTPRD EM Info THP-1 monocytes cg14439952 . [4], [5]
DNA Hypermethylation PTPRF EM Info THP-1 monocytes cg00014445 . [4], [5]
DNA Hypermethylation PTPRN2 EM Info THP-1 monocytes cg00235442 . [4], [5]
DNA Hypermethylation PYCARD EM Info THP-1 monocytes cg09055507 . [4], [5]
DNA Hypermethylation RAB11FIP3 EM Info THP-1 monocytes cg01005536 . [4], [5]
DNA Hypermethylation RAB27A EM Info THP-1 monocytes cg25490585 . [4], [5]
DNA Hypermethylation RAB3IP EM Info THP-1 monocytes cg00499750 . [4], [5]
DNA Hypermethylation RALGPS1 EM Info THP-1 monocytes cg14025518 . [4], [5]
DNA Hypermethylation RANGAP1 EM Info THP-1 monocytes cg20978858 . [4], [5]
DNA Hypermethylation RASGRP3 EM Info THP-1 monocytes cg17735563 . [4], [5]
DNA Hypermethylation RBM19 EM Info THP-1 monocytes cg13621101 . [4], [5]
DNA Hypermethylation RBM22 EM Info THP-1 monocytes cg22486051 . [4], [5]
DNA Hypermethylation RBPJL EM Info THP-1 monocytes cg06302806 . [4], [5]
DNA Hypermethylation REXO1 EM Info THP-1 monocytes cg11622330 . [4], [5]
DNA Hypermethylation RHBDF2 EM Info THP-1 monocytes cg21028211 . [4], [5]
DNA Hypermethylation RHOU EM Info THP-1 monocytes cg07838098 . [4], [5]
DNA Hypermethylation RING1 EM Info THP-1 monocytes cg18189601 . [4], [5]
DNA Hypermethylation RIPK1 EM Info THP-1 monocytes cg06367140 . [4], [5]
DNA Hypermethylation RNF113A EM Info THP-1 monocytes cg08841290 . [4], [5]
DNA Hypermethylation RPAP1 EM Info THP-1 monocytes cg07976408 . [4], [5]
DNA Hypermethylation RPL23P8 EM Info THP-1 monocytes cg05068035 . [4], [5]
DNA Hypermethylation RPS6KA2 EM Info THP-1 monocytes cg17087907 . [4], [5]
DNA Hypermethylation RPTOR EM Info THP-1 monocytes cg22636722 . [4], [5]
DNA Hypermethylation RPTOR EM Info THP-1 monocytes cg24667756 . [4], [5]
DNA Hypermethylation RTN3 EM Info THP-1 monocytes cg08242020 . [4], [5]
DNA Hypermethylation S1PR1 EM Info THP-1 monocytes cg23978968 . [4], [5]
DNA Hypermethylation SCML4 EM Info THP-1 monocytes cg23369647 . [4], [5]
DNA Hypermethylation SERBP1 EM Info THP-1 monocytes cg11697983 . [4], [5]
DNA Hypermethylation SERTAD1 EM Info THP-1 monocytes cg13542022 . [4], [5]
DNA Hypermethylation SETD1B EM Info THP-1 monocytes cg10331528 . [4], [5]
DNA Hypermethylation SFRP2 EM Info THP-1 monocytes cg23502475 . [4], [5]
DNA Hypermethylation SHANK2 EM Info THP-1 monocytes cg10768900 . [4], [5]
DNA Hypermethylation SHANK2 EM Info THP-1 monocytes cg21202716 . [4], [5]
DNA Hypermethylation SKI EM Info THP-1 monocytes cg26264656 . [4], [5]
DNA Hypermethylation SLAIN1 EM Info THP-1 monocytes cg20094321 . [4], [5]
DNA Hypermethylation SLAMF1 EM Info THP-1 monocytes cg21829239 . [4], [5]
DNA Hypermethylation SLC12A7 EM Info THP-1 monocytes cg04725215 . [4], [5]
DNA Hypermethylation SLC18A2 EM Info THP-1 monocytes cg10245915 . [4], [5]
DNA Hypermethylation SLC1A2 EM Info THP-1 monocytes cg25230151 . [4], [5]
DNA Hypermethylation SLC22A23 EM Info THP-1 monocytes cg08754725 . [4], [5]
DNA Hypermethylation SLC24A1 EM Info THP-1 monocytes cg07116160 . [4], [5]
DNA Hypermethylation SLC25A29 EM Info THP-1 monocytes cg24141378 . [4], [5]
DNA Hypermethylation SLC2A5 EM Info THP-1 monocytes cg00690929 . [4], [5]
DNA Hypermethylation SLC34A2 EM Info THP-1 monocytes cg01493016 . [4], [5]
DNA Hypermethylation SLC34A2 EM Info THP-1 monocytes cg02272859 . [4], [5]
DNA Hypermethylation SLC45A3 EM Info THP-1 monocytes cg12178904 . [4], [5]
DNA Hypermethylation SLC6A19 EM Info THP-1 monocytes cg03807914 . [4], [5]
DNA Hypermethylation SLC6A4 EM Info THP-1 monocytes cg05016953 . [4], [5]
DNA Hypermethylation SLC6A6 EM Info THP-1 monocytes cg08655589 . [4], [5]
DNA Hypermethylation SMARCD3 EM Info THP-1 monocytes cg02419716 . [4], [5]
DNA Hypermethylation SMO EM Info THP-1 monocytes cg04478795 . [4], [5]
DNA Hypermethylation SNRK EM Info THP-1 monocytes cg15328005 . [4], [5]
DNA Hypermethylation SNRPC EM Info THP-1 monocytes cg04506628 . [4], [5]
DNA Hypermethylation SNX16 EM Info THP-1 monocytes cg24320091 . [4], [5]
DNA Hypermethylation SNX2 EM Info THP-1 monocytes cg17591829 . [4], [5]
DNA Hypermethylation SORCS2 EM Info THP-1 monocytes cg05144635 . [4], [5]
DNA Hypermethylation SPANXN3 EM Info THP-1 monocytes cg12127356 . [4], [5]
DNA Hypermethylation SPDYE5 EM Info THP-1 monocytes cg11910105 . [4], [5]
DNA Hypermethylation SSR3 EM Info THP-1 monocytes cg04798497 . [4], [5]
DNA Hypermethylation ST7 EM Info THP-1 monocytes cg00764217 . [4], [5]
DNA Hypermethylation STAM2 EM Info THP-1 monocytes cg12053532 . [4], [5]
DNA Hypermethylation STIM1 EM Info THP-1 monocytes cg26296653 . [4], [5]
DNA Hypermethylation STXBP1 EM Info THP-1 monocytes cg00560119 . [4], [5]
DNA Hypermethylation STXBP2 EM Info THP-1 monocytes cg24433207 . [4], [5]
DNA Hypermethylation SYF2 EM Info THP-1 monocytes cg22856539 . [4], [5]
DNA Hypermethylation TAL1 EM Info THP-1 monocytes cg01147107 . [4], [5]
DNA Hypermethylation TANC2 EM Info THP-1 monocytes cg18366149 . [4], [5]
DNA Hypermethylation TBC1D1 EM Info THP-1 monocytes cg19090437 . [4], [5]
DNA Hypermethylation TBC1D10C EM Info THP-1 monocytes cg00220455 . [4], [5]
DNA Hypermethylation TBC1D14 EM Info THP-1 monocytes cg19906672 . [4], [5]
DNA Hypermethylation TBCE EM Info THP-1 monocytes cg26931960 . [4], [5]
DNA Hypermethylation TCERG1L EM Info THP-1 monocytes cg20224780 . [4], [5]
DNA Hypermethylation TCF7L2 EM Info THP-1 monocytes cg15807455 . [4], [5]
DNA Hypermethylation TCTEX1D1 EM Info THP-1 monocytes cg14207728 . [4], [5]
DNA Hypermethylation TET1 EM Info THP-1 monocytes cg22876739 . [4], [5]
DNA Hypermethylation TEX11 EM Info THP-1 monocytes cg17537844 . [4], [5]
DNA Hypermethylation TFAP2D EM Info THP-1 monocytes cg21760402 . [4], [5]
DNA Hypermethylation THBS1 EM Info THP-1 monocytes cg00836101 . [4], [5]
DNA Hypermethylation THEG EM Info THP-1 monocytes cg05330259 . [4], [5]
DNA Hypermethylation THSD4 EM Info THP-1 monocytes cg24957704 . [4], [5]
DNA Hypermethylation TIRAP EM Info THP-1 monocytes cg06263077 . [4], [5]
DNA Hypermethylation TLX1 EM Info THP-1 monocytes cg00741609 . [4], [5]
DNA Hypermethylation TM9SF3 EM Info THP-1 monocytes cg00606464 . [4], [25]
DNA Hypermethylation TMCO3 EM Info THP-1 monocytes cg09537621 . [4], [26]
DNA Hypermethylation TMED1 EM Info THP-1 monocytes cg08100233 . [4], [5]
DNA Hypermethylation TMEM150A EM Info THP-1 monocytes cg15613465 . [4], [5]
DNA Hypermethylation TMEM211 EM Info THP-1 monocytes cg18946437 . [4], [5]
DNA Hypermethylation TMEM33 EM Info THP-1 monocytes cg07207957 . [4], [5]
DNA Hypermethylation TMEM91 EM Info THP-1 monocytes cg25798605 . [4], [5]
DNA Hypermethylation TNF EM Info THP-1 monocytes cg12681001 . [4], [5]
DNA Hypermethylation TNFRSF10A EM Info THP-1 monocytes cg01725531 . [4], [5]
DNA Hypermethylation TOP1MT EM Info THP-1 monocytes cg24789335 . [4], [5]
DNA Hypermethylation TPRG1L EM Info THP-1 monocytes cg13059495 . [4], [5]
DNA Hypermethylation TPRG1L EM Info THP-1 monocytes cg20433829 . [4], [5]
DNA Hypermethylation TPRXL EM Info THP-1 monocytes cg09623510 . [4], [5]
DNA Hypermethylation TPSD1 EM Info THP-1 monocytes cg08071282 . [4], [5]
DNA Hypermethylation TREML2 EM Info THP-1 monocytes cg27193858 . [4], [5]
DNA Hypermethylation TREML2P EM Info THP-1 monocytes cg16231757 . [4], [5]
DNA Hypermethylation TRIL EM Info THP-1 monocytes cg24426072 . [4], [5]
DNA Hypermethylation TRIM11 EM Info THP-1 monocytes cg08468679 . [4], [5]
DNA Hypermethylation TRIM17 EM Info THP-1 monocytes cg20939768 . [4], [5]
DNA Hypermethylation TRIM27 EM Info THP-1 monocytes cg17344091 . [4], [5]
DNA Hypermethylation TRIM45 EM Info THP-1 monocytes cg24335302 . [4], [5]
DNA Hypermethylation TSGA10 EM Info THP-1 monocytes cg25411534 . [4], [5]
DNA Hypermethylation TTC27 EM Info THP-1 monocytes cg08735990 . [4], [5]
DNA Hypermethylation TTLL5 EM Info THP-1 monocytes cg23920251 . [4], [5]
DNA Hypermethylation TTLL8 EM Info THP-1 monocytes cg00117914 . [4], [5]
DNA Hypermethylation UBAP2L EM Info THP-1 monocytes cg11248189 . [4], [5]
DNA Hypermethylation UBE2E1 EM Info THP-1 monocytes cg19719475 . [4], [5]
DNA Hypermethylation UFM1 EM Info THP-1 monocytes cg03558682 . [4], [5]
DNA Hypermethylation UNKL EM Info THP-1 monocytes cg06876040 . [4], [5]
DNA Hypermethylation USP38 EM Info THP-1 monocytes cg24251135 . [4], [5]
DNA Hypermethylation UST EM Info THP-1 monocytes cg23828170 . [4], [5]
DNA Hypermethylation VRK2 EM Info THP-1 monocytes cg07227049 . [4], [5]
DNA Hypermethylation WASL EM Info THP-1 monocytes cg10254872 . [4], [5]
DNA Hypermethylation WDR59 EM Info THP-1 monocytes cg04871835 . [4], [5]
DNA Hypermethylation WHSC1 EM Info THP-1 monocytes cg19163818 . [4], [5]
DNA Hypermethylation YTHDC1 EM Info THP-1 monocytes cg01804429 . [4], [5]
DNA Hypermethylation YWHAQ EM Info THP-1 monocytes cg18861713 . [4], [5]
DNA Hypermethylation ZC3HAV1 EM Info THP-1 monocytes cg23424043 . [4], [5]
DNA Hypermethylation ZCCHC14 EM Info THP-1 monocytes cg07205670 . [4], [5]
DNA Hypermethylation ZDHHC14 EM Info THP-1 monocytes cg10378795 . [4], [5]
DNA Hypermethylation ZFYVE9 EM Info THP-1 monocytes cg24482202 . [4], [5]
DNA Hypermethylation ZMIZ1 EM Info THP-1 monocytes cg23802518 . [4], [5]
DNA Hypermethylation ZMYM3 EM Info THP-1 monocytes cg21380015 . [4], [5]
DNA Hypermethylation ZNF292 EM Info THP-1 monocytes cg06456538 . [4], [5]
DNA Hypermethylation ZNF317 EM Info THP-1 monocytes cg19358348 . [4], [5]
DNA Hypermethylation ZNF362 EM Info THP-1 monocytes cg02972475 . [4], [5]
DNA Hypermethylation ZNF365 EM Info THP-1 monocytes cg00113225 . [4], [5]
DNA Hypermethylation ZNF451 EM Info THP-1 monocytes cg26891999 . [4], [5]
DNA Hypermethylation ZNF492 EM Info THP-1 monocytes cg18599790 . [4], [5]
DNA Hypermethylation ZNF503 EM Info THP-1 monocytes cg08158570 . [4], [5]
DNA Hypermethylation ZNF512 EM Info THP-1 monocytes cg18883643 . [4], [5]
DNA Hypermethylation ZNF516 EM Info THP-1 monocytes cg07783458 . [4], [5]
DNA Hypermethylation ZNF583 EM Info THP-1 monocytes cg11718235 . [4], [5]
DNA Hypermethylation ZNF605 EM Info THP-1 monocytes cg11807290 . [4], [5]
DNA Hypermethylation ZNF649 EM Info THP-1 monocytes cg27175069 . [4], [5]
DNA Hypermethylation ZNF652 EM Info THP-1 monocytes cg07164631 . [4], [5]
DNA Hypermethylation ZNF697 EM Info THP-1 monocytes cg00482226 . [4], [5]
DNA Hypermethylation ZNF710 EM Info THP-1 monocytes cg16785520 . [4], [5]
DNA Hypermethylation ZXDC EM Info THP-1 monocytes cg15825032 . [4], [5]
Histone Deacetylation SIRT1 EM Info . . . [1], [4]

The microbes that produce this metabolite
      Roseburia
         Detailed Information MIC Info click to show the detail information of this Microbiota [4]
         Description
Roseburia is a genus of butyrate-producing, gram-positive anaerobic bacteria that inhabit the human colon.
      Clostridium
         Detailed Information MIC Info click to show the detail information of this Microbiota [1], [4]
         Description
Clostridium is a genus of gram-positive, anaerobic bacteria from the family Bacillaceae.
      Bifidobacterium
         Detailed Information MIC Info click to show the detail information of this Microbiota [1], [4]
         Description
Bifidobacteria is a genus of gram-positive, nonmotile, often branched anaerobic bacteria. They are ubiquitous inhabitants of the gastrointestinal tract, vagina and mouth of mammals, including humans.
      Klebsiella
         Detailed Information MIC Info click to show the detail information of this Microbiota [4]
         Description
Klebsiella is a genus of gram-negative, oxidase-negative, rod-shaped bacteria from the family Enterobacteriaceae
      Enterobacter
         Detailed Information MIC Info click to show the detail information of this Microbiota [4]
         Description
Enterobacter is a genus of common gram-negative, facultatively anaerobic, rod-shaped, non-spore-forming bacteria of the family Enterobacteriaceae. It is the type genus of the order Enterobacterales.
      Citrobacter
         Detailed Information MIC Info click to show the detail information of this Microbiota [4]
         Description
Citrobacter is a genus of gram-negative coliform bacteria in the family Enterobacteriaceae. The species C. amalonaticus, C. koseri, and C. freundii can use citrate as a sole carbon source. Citrobacter species are differentiated by their ability to convert tryptophan to indole, ferment lactose, and use malonate.
      Lactobacillus
         Detailed Information MIC Info click to show the detail information of this Microbiota [4]
         Description
Lactobacillus is a genus of gram-positive, facultative anaerobic or microaerophilic, rod-shaped, non-spore-forming bacteria. They are a major part of the lactic acid bacteria group. In humans, they constitute a significant component of the microbiota at a number of body sites, such as the digestive system, urinary system, and genital system.

References
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2 Dietary proline supplementation alters colonic luminal microbiota and bacterial metabolite composition between days 45 and 70 of pregnancy in Huanjiang mini-pigs J Anim Sci Biotechnol. 2018 Jan 30;9:18. doi: 10.1186/s40104-018-0233-5. eCollection 2018.
3 Blood Pressure Abnormalities Associated with Gut Microbiota-Derived Short Chain Fatty Acids in Children with Congenital Anomalies of the Kidney and Urinary Tract J Clin Med. 2019 Jul 24;8(8):1090. doi: 10.3390/jcm8081090.
4 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
5 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.
6 c-Abl kinase regulates neutrophil extracellular trap formation, inflammation, and tissue damage in severe acute pancreatitis. J Leukoc Biol. 2019 Aug;106(2):455-466. doi: 10.1002/JLB.3A0618-222RR. Epub 2019 Mar 12.
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10 Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis. 2008 Sep;29(9):1765-73. doi: 10.1093/carcin/bgn074. Epub 2008 Mar 13.
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13 Phenylbutyrate and phenylacetate induce differentiation and inhibit proliferation of human medulloblastoma cells. Clin Cancer Res. 2004 Feb 1;10(3):1150-9. doi: 10.1158/1078-0432.ccr-0747-3.
14 Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3. Hum Mol Genet. 2013 Jul 1;22(13):2662-75. doi: 10.1093/hmg/ddt115. Epub 2013 Mar 7.
15 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
16 Antimicrobial production by strictly anaerobic Clostridium spp Int J Antimicrob Agents. 2020 May;55(5):105910. doi: 10.1016/j.ijantimicag.2020.105910. Epub 2020 Jan 25.
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19 Synergistic Effect in Core Microbiota Associated with Sulfur Metabolism in Spontaneous Chinese Liquor Fermentation Appl Environ Microbiol. 2017 Dec 1;83(24):e01475-17. doi: 10.1128/AEM.01475-17. Print 2017 Dec 15.
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21 Stages of pregnancy and weaning influence the gut microbiota diversity and function in sows J Appl Microbiol. 2019 Sep;127(3):867-879. doi: 10.1111/jam.14344. Epub 2019 Jul 1.
22 Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression. PLoS One. 2012;7(6):e39501. doi: 10.1371/journal.pone.0039501. Epub 2012 Jun 20.
23 Lysine benzoylation is a histone mark regulated by SIRT2. Nat Commun. 2018 Aug 28;9(1):3374. doi: 10.1038/s41467-018-05567-w.
24 Response of MiRNA-22-3p and MiRNA-149-5p to Folate Deficiency and the Differential Regulation of MTHFR Expression in Normal and Cancerous Human Hepatocytes. PLoS One. 2017 Jan 3;12(1):e0168049. doi: 10.1371/journal.pone.0168049. eCollection 2017.
25 Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster. J Nutr. 2008 Dec;138(12):2316-22. doi: 10.3945/jn.108.098673.
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27 Intermediaries of branched chain amino acid metabolism induce fetal hemoglobin, and repress SOX6 and BCL11A, in definitive erythroid cells. Blood Cells Mol Dis. 2015 Aug;55(2):161-7. doi: 10.1016/j.bcmd.2015.05.006. Epub 2015 May 27.

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