Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM11885) | |||||||
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| Official Symbol |
ATP11A
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| Official Full Name |
ATPase Phospholipid Transporting 11A
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| Synonym |
ATPase, Class VI, Type 11A
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr13(Start:112690034 - End:112690034)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2C30: Melanoma of skin | Cutaneous Melanoma [Melanoma of skin] | ||||||
| Detailed Information |
Disease Link
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| 5A02: Thyrotoxicosis | Graves' disease [Thyrotoxicosis] | ||||||
| Detailed Information |
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| 6B01: Panic disorder | Panic Disorder [Panic disorder] | ||||||
| Detailed Information |
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| 8A00: Parkinsonism | Parkinson's disease (PD) [Parkinsonism] | ||||||
| Detailed Information |
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| 8A01: Choreiform disorders | Huntington's disease (HD) [Choreiform disorders] | ||||||
| Detailed Information |
Disease Link
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| CB03: Idiopathic interstitial pneumonitis | Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis] | ||||||
| Detailed Information |
Disease Link
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| FB83: Low bone mass disorders | Primary osteoporosis [Low bone mass disorders] | ||||||
| Detailed Information |
Disease Link
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| LD2C: Overgrowth syndromes | Sotos syndrome(SS) [Overgrowth syndromes] | ||||||
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Disease Link
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| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
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Disease Link
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| XH4XG8: Chronic myeloid leukaemia | Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia] | ||||||
| Detailed Information |
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| XH5QN3: Nephroblastoma | Wilms tumor [Nephroblastoma] | ||||||
| Detailed Information |
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| ZERO(Not Found): Kagami-Ogata syndrome | KOS14: Kagami-Ogata syndrome [Kagami-Ogata syndrome] | ||||||
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Disease Link
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| Metabolite(s) with this epigenetic modification | |||||||
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| Metabolite Name: Arachidonic acid | |||||||
| Detailed Information |
Meta Info
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[1] | |||||
| Description |
Arachidonic acid could induce ATP11A gene hypermethylation in THP-1 cells.
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| References | |||||
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| 1 | Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597. | ||||
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