Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11912)
  Official Symbol
LINC00301
  Official Full Name
Long Intergenic Non-Protein Coding RNA 301
  Synonym
Long Intergenic Non-Protein Coding RNA 301;Long Intergenic Non-Protein Coding RNA 301;NCRNA00301;C11orf64;MGC39681;Putative Uncharacterized Protein Encoded By LINC00301;Chromosome 11 Open Reading Frame 64;Non-Protein Coding RNA 301;NONHSAG008435.2;Lnc-MS4A8-17
  Molecule Type
Protein coding
  Position On Chromosome
chr11(Start:60587751 - End:60687297)
  Strand
+
  Uniprot Entry
Q8NCQ3 
  ENSG ID
ENSG00000181995 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
            Detailed Information Disease Link click to show the detail information of this Disease
         SE30: Developmental delay disorder CHARGE and Kabuki syndromes [Developmental delay disorder]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH4XG8: Chronic myeloid leukaemia Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce C11orf64 gene hypermethylation in THP-1 cells.

References
1 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
2 Antimicrobial production by strictly anaerobic Clostridium spp Int J Antimicrob Agents. 2020 May;55(5):105910. doi: 10.1016/j.ijantimicag.2020.105910. Epub 2020 Jan 25.

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