Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11933)
  Official Symbol
FAM209B
  Official Full Name
Family With Sequence Similarity 209 Member B
  Synonym
Family With Sequence Similarity 209 Member B;DJ1153D9.4;C20orf107;Protein FAM209B;Family With Sequence Similarity 209, Member B;Chromosome 20 Open Reading Frame 107;Uncharacterized Protein C20orf107
  Molecule Type
Protein coding
  Position On Chromosome
chr20(Start:56527124 - End:56555626)
  Strand
+
  Uniprot Entry
Q5JX69 
  ENSG ID
ENSG00000213714 
    Disease Relevance (Click to Show/Hide)
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce C20orf107 gene hypermethylation in THP-1 cells.

References
1 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
2 Antimicrobial production by strictly anaerobic Clostridium spp Int J Antimicrob Agents. 2020 May;55(5):105910. doi: 10.1016/j.ijantimicag.2020.105910. Epub 2020 Jan 25.

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