Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11978)
  Official Symbol
CGB8
  Official Full Name
Chorionic Gonadotropin Subunit Beta 8
  Synonym
Chorionic Gonadotropin, Beta Polypeptide 8;Chorionic Gonadotropin Subunit Beta 8;Chorionic Gonadotropin Beta Subunit 8;Chorionic Gonadotropin Beta 8 Subunit;Choriogonadotropin Subunit Beta;CGB;Chorionic Gonadotropin Chain Beta
  Molecule Type
Protein coding
  Position On Chromosome
chr19(Start:49047638 - End:49049111)
  Strand
-
  Uniprot Entry
P0DN86 
  ENSG ID
ENSG00000213030 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         SE30: Developmental delay disorder CHARGE and Kabuki syndromes [Developmental delay disorder]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce CGB8 gene hypermethylation in THP-1 cells.

References
1 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.
2 Stages of pregnancy and weaning influence the gut microbiota diversity and function in sows J Appl Microbiol. 2019 Sep;127(3):867-879. doi: 10.1111/jam.14344. Epub 2019 Jul 1.

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