Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12221)
  Official Symbol
MIR487A
  Official Full Name
MicroRNA 487a
  Synonym
Hsa-Mir-487a;Hsa-Mir-487;MIRN487;Hsa-Mir-154-P16;Hsa-Mir-154-P16;Hsa-MiR-487a-5p;MIMAT0026559;MI0002471;Mir-487a;RF00641
  Molecule Type
RNA Gene
  Position On Chromosome
chr14(Start:101052446 - End:101052525)
  Strand
+
  ENSG ID
ENSG00000207742 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A00: Parkinsonism Parkinson's disease (PD) [Parkinsonism]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce MIR487A gene hypermethylation in THP-1 cells.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

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