General Information of EM (ID: EM12396)
  Official Symbol
SLC2A5
  Official Full Name
Solute Carrier Family 2 Member 5
  Synonym
Solute Carrier Family 2 Member 5;GLUT5;Solute Carrier Family 2 (Facilitated Glucose/Fructose Transporter), Member 5;Solute Carrier Family 2, Facilitated Glucose Transporter Member 5;Glucose Transporter-Like Protein 5;Testicular Tissue Protein Li 81;Fructose Transporter
  Molecule Type
Protein coding
  Position On Chromosome
chr1(Start:9035106 - End:9088478)
  Strand
-
  Uniprot Entry
P22732 
  ENSG ID
ENSG00000142583 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         5A02: Thyrotoxicosis Graves' disease [Thyrotoxicosis]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A00: Parkinsonism Parkinson's disease (PD) [Parkinsonism]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A01: Choreiform disorders Huntington's disease (HD) [Choreiform disorders]
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         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         CB03: Idiopathic interstitial pneumonitis Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis]
            Detailed Information Disease Link click to show the detail information of this Disease
         DD70: Crohn disease Crohn's disease [Crohn disease]
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         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
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         XH4KA9: Burkitt lymphoma Burkitt Lymphoma [Burkitt lymphoma]
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         XH4XG8: Chronic myeloid leukaemia Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia]
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         ZERO(Not Found): Glomerular diseases IgA nephropathy [Glomerular diseases]
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Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce SLC2A5 gene hypermethylation in THP-1 cells.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

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