Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12007)
  Official Symbol
CSN1S1
  Official Full Name
Casein Alpha S1
  Synonym
CASA;Casein Alpha S1;CSN1;Alpha-S1-Casein;Casein, Alpha
  Molecule Type
Protein coding
  Position On Chromosome
chr4(Start:69931062 - End:69946574)
  Strand
+
  Uniprot Entry
P47710 
  ENSG ID
ENSG00000126545 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         6B01: Panic disorder Panic Disorder [Panic disorder]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Arachidonic acid
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Arachidonic acid could induce CSN1S1 gene hypermethylation in THP-1 cells.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Lysine benzoylation is a histone mark regulated by SIRT2. Nat Commun. 2018 Aug 28;9(1):3374. doi: 10.1038/s41467-018-05567-w.

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