Details of Metabolite (Meta)

General Information of Metabolite (ID: MT031)
Meta Name		Phenolic acid
Unify Name		Phenolic acid
Molecule Type		Phenolic compounds
Description		Click to Show/Hide the Detailed Description of This Metabolite Phenolic acids or phenolcarboxylic acids are types of aromatic acid compound. Included in that class are substances containing a phenolic ring and an organic carboxylic acid function. Two important naturally occurring types of phenolic acids are hydroxybenzoic acids and hydroxycinnamic acids, which are derived from non-phenolic molecules of benzoic and cinnamic acid, respectively.

The epigenetic modification information of this metabolite
Modification Type																				Molecule																				EM Info								Cell/Tissue Type																		Modified sites																						Condition														REF
DNA Methylation																				DNMT																				EM Info								.																		.																						.														[1], [2]

The microbes that produce this metabolite
Escherichia coli
Detailed Information	MIC Info click to show the detail information of this Microbiota	[3], [4]
Description	Escherichia coli, also known as E. coli, is a gram-negative, facultative anaerobic, rod-shaped, coliform bacteria of the genus Escherichia.
Bifidobacterium bifidum
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Bifidobacteria bifidum is a bacterial species of the genus Bifidobacteria. B. bifidum is one of the most common probiotic bacteria that can be found in the body of mammals, including humans.
Bacteroides fragilis
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Bacteroides fragilis is an obligately anaerobic, gram-negative, rod-shaped bacteria. It is part of the normal microbiota of the human colon and is generally commensal, but can cause infection if displaced into the bloodstream or surrounding tissue following surgery, disease or trauma.
Bacteroides thetaiotaomicron
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Bacteroides thetaiotaomicron is a species of bacteria of the genus Bacteroides. It is a gram-negative obligate anaerobic. It is one of the most common bacteria found in human gut microbiota and is also an opportunistic pathogen.
Lactobacillus fermentum
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Lactobacillus fermentum (Lb. fermentum) is a gram-positive bacteria belonging to Lactobacillus genus, and many reportedly to enhance the immunologic response as well as prevent community-acquired gastrointestinal and upper respiratory infections.
Clostridium perfringens
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Clostridium perfringens is an anaerobic, gram-positive, spore-forming, rod-shaped pathogenic bacteria of the genus Clostridium.
Serratia marcescens
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Serratia marcescens is a species of rod-shaped, gram-negative bacteria in the family Yersiniaceae. It is a facultative anaerobic and an opportunistic pathogen.
Acinetobacter baumannii
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Acinetobacter baumannii (A. baumannii) is a gram-negative, aerobic bacteria, which belongs to the family Neisseriaceae.
Eubacterium lentum
Detailed Information	MIC Info click to show the detail information of this Microbiota	[1], [2]
Description	Eubacterium lentum is the species that is most often isolated; it has been linked to endocarditis. Biochemical testing can distinguish Eubacterium from the other gram-positive, anaerobic rods.

References
1	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2	Effect of phenolic acids of microbial origin on production of reactive oxygen species in mitochondria and neutrophils J Biomed Sci. 2012 Oct 12;19(1):89. doi: 10.1186/1423-0127-19-89.
3	S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression. Cells. 2020 Aug 9;9(8):1864. doi: 10.3390/cells9081864.
4	Progress in the microbial production of S-adenosyl-L-methionine World J Microbiol Biotechnol. 2016 Sep;32(9):153. doi: 10.1007/s11274-016-2102-8. Epub 2016 Jul 27.

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