| General Information of MIC (ID: MC0939) |
| MIC Name |
Bacteroides caccae
|
| Lineage |
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
|
| Oxygen Sensitivity |
Anaerobe
|
| Microbial Metabolism |
Saccharolytic; Fermentative
|
| Gram |
Negative
|
| Host Relationship |
Commensal
|
| Genome Size (bp) |
4564814
|
| Description |
Bacteroides caccae is a saccharolytic gram-negative bacteria from the genus Bacteroides. They are obligate anaerobics first isolated from human feces in the 1980s.
|
| External Links |
Taxonomy ID |
47678
|
| GutMDisorder ID |
gm0079
|
| Genome Assembly ID |
ASM16901v1
|
| GOLD Database ID |
Go0000883
|
| GIMICA ID |
MIC00148
|
| Full List of Metabolite(s) Produced by This MIC |
| Molecule Type: Microbial cell components |
|---|
| Metabolite Name: Lipopolysaccharide |
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|
| Detailed Infomation |
Meta Info
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|
Metabolic Classification |
Microbial cell components |
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| DNA Methylation |
DNMT3A |
EM Info
|
. |
. |
. |
[1], [2] |
| DNA Methylation |
DNMT3B |
EM Info
|
. |
. |
. |
[1], [2] |
| DNA Methylation |
DNMT1 |
EM Info
|
Oral epithelial cells |
. |
Periodontitis |
[2], [3] |
| Histone Acetylation |
H4 |
EM Info
|
. |
. |
. |
[1], [2] |
| Histone Acetylation |
Histone |
EM Info
|
TGF-beta1 cells |
lysine 9 |
. |
[2], [4] |
| Histone Acetylation |
H3 |
EM Info
|
Oral epithelial cells |
lysine 9 |
Periodontitis |
[2], [3] |
| Histone Deacetylation |
HDAC6 |
EM Info
|
. |
. |
. |
[1], [2] |
| Histone Deacetylation |
HDAC7 |
EM Info
|
. |
. |
. |
[1], [2] |
| Histone Phosphorylation |
Histone |
EM Info
|
TGF-beta1 cells |
serine 10 |
. |
[2], [4] |
| References |
| 1 |
Dietary metabolites derived from gut microbiota: critical modulators of epigenetic changes in mammals. Nutr Rev. 2017 May 1;75(5):374-389. doi: 10.1093/nutrit/nux001.
|
| 2 |
Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling mSystems. 2017 Nov 14;2(6):e00046-17. doi: 10.1128/mSystems.00046-17. eCollection 2017 Nov-Dec.
|
| 3 |
Epigenetic Modifications of Histones in Periodontal Disease. J Dent Res. 2016 Feb;95(2):215-22. doi: 10.1177/0022034515611876. Epub 2015 Oct 23.
|
| 4 |
Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation J Biol Chem. 2003 Jun 27;278(26):23851-60. doi: 10.1074/jbc.M300075200. Epub 2003 Apr 2.
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