Details of Microbe Species (MIC)

General Information of MIC (ID: MC0744)
  MIC Name
Bifidobacterium adolescentis
  Synonym
Bifidobacterium stercoris
  Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
  Oxygen Sensitivity
Obligate anaerobe
  Microbial Metabolism
Saccharolytic; Fermentative
  Gram
Positive
  Host Relationship
Probiotic
  Genome Size (bp)
2203222
  No. of Coding Genes
1725
  No. of Non-Coding Genes
67
  No. of Small Non-Coding Genes
67
  No. of Gene Transcripts
1792
  No. of Base Pairs
2203222
  Description
Bifidobacteria adolescentis is a gram-positive bacteria that has no spores, no flagella, and does not move.
  External Links Taxonomy ID 1680
GutMDisorder ID gm0106
Genome Assembly ID ASM73788v1
GOLD Database ID Go0517356
GIMICA ID MIC00205

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Amino acid (AAs)
           Metabolite Name: Phenylacetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [precursors]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Deacetylation HDAC EM Info . . . [1], [2]
     Molecule Type: Fatty acids
           Metabolite Name: Butyrate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA Demethylation POU5F1 EM Info iPS cells promoter . [3], [2]
DNA Demethylation DPPA2 EM Info iPS cells promoter . [4], [2]
Histone Acetylation H3 EM Info CD41T cells Foxo3A promoter . [5], [2]
Histone Crotonylation H3K9 EM Info KGN cells GPR43 . [1], [2]
Histone Deacetylation HDAC1 EM Info . . . [5], [6]
Histone Deacetylation HDAC2 EM Info . . . [5], [2]
miRNA miR-92a EM Info Colon cancer cells . Colon cancer [5], [7]
     Molecule Type: Vitamins
           Metabolite Name: Riboflavin (B2) Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [precursors]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA Methylation Zac1 EM Info . . . [8], [2]


References
1 Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells. 2010 Apr;28(4):713-20. doi: 10.1002/stem.402.
2 The Gut Microbiota from Lean and Obese Subjects Contribute Differently to the Fermentation of Arabinogalactan and Inulin PLoS One. 2016 Jul 13;11(7):e0159236. doi: 10.1371/journal.pone.0159236. eCollection 2016.
3 Crosstalk between the microbiome and epigenome: messages from bugs. J Biochem. 2018 Feb 1;163(2):105-112. doi: 10.1093/jb/mvx080.
4 Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature. 2013 Dec 19;504(7480):446-50. doi: 10.1038/nature12721. Epub 2013 Nov 13.
5 Dietary metabolites derived from gut microbiota: critical modulators of epigenetic changes in mammals. Nutr Rev. 2017 May 1;75(5):374-389. doi: 10.1093/nutrit/nux001.
6 p-Cresyl Sulfate. Toxins (Basel). 2017 Jan 29;9(2):52. doi: 10.3390/toxins9020052.
7 The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity PLoS Genet. 2009 Dec;5(12):e1000785. doi: 10.1371/journal.pgen.1000785. Epub 2009 Dec 24.
8 Butyrate drives the acetylation of histone H3K9 to activate steroidogenesis through PPAR-gamma and PGC1-alpha pathways in ovarian granulosa cells. FASEB J. 2021 Feb;35(2):e21316. doi: 10.1096/fj.202000444R.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.