Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10022)
  Official Symbol
PLAGL1
  Official Full Name
PLAG1 like zinc finger 1
  Synonym
LOT1;ZAC
  Molecule Type
Protein coding
  Position On Chromosome
chr6(Start:143940300 - End:144064599)
  Strand
-
  Uniprot Entry
Q9UM63 
  ENSG ID
ENSG00000118495 
  Dnmivd Disease
UCEC 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Riboflavin (B2)
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
RIboflavin (B2) has been shown to increase methylation of the ZAC1 gene.

References
1 Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis. 2008 Sep;29(9):1765-73. doi: 10.1093/carcin/bgn074. Epub 2008 Mar 13.
2 Biosynthesis of Vitamins by Probiotic Bacteria.

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