Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10077)
Official Symbol		MIR92A1
Official Full Name		microRNA 92a-1
Synonym		MIRN92-1;MIRN92A1;hsa-mir-92-1;hsa-mir-92a-1
Molecule Type		miRNA
Position On Chromosome		chr13(Start:91351314 - End:91351391)
Strand		+
ENSG ID		ENSG00000283705
Dnmivd Disease		BLCA

Metabolite(s) with this epigenetic modification
Metabolite Name: Butyrate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Butyrate appeared to function as a tumour suppressor andcould decrease colon cancer cell proliferation and stimulate apoptosis through inhibition of miR-92a transcription.

References
1	Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation J Biol Chem. 2003 Jun 27;278(26):23851-60. doi: 10.1074/jbc.M300075200. Epub 2003 Apr 2.
2	Epigenetic Modifications of Histones in Periodontal Disease. J Dent Res. 2016 Feb;95(2):215-22. doi: 10.1177/0022034515611876. Epub 2015 Oct 23.

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