Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM14180)
Official Symbol		POU5F1
Official Full Name		POU class 5 homeobox 1
Synonym		OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; Oct3/4
Molecule Type		Protein coding
Position On Chromosome		chr6(Start:31164337 - End:31180731)
Strand		-
Uniprot Entry		Q01860
ENSG ID		ENSG00000204531

Metabolite(s) with this epigenetic modification
Metabolite Name: Butyrate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Butyrate has been shown to promote the demethylation of POU5F1 promoter.

References
1	Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells. 2010 Apr;28(4):713-20. doi: 10.1002/stem.402.
2	Characterization a Novel Butyric Acid-Producing Bacterium Collinsella aerofaciens Subsp. Shenzhenensis Subsp. Nov Microorganisms. 2019 Mar 13;7(3):78. doi: 10.3390/microorganisms7030078.

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