Details of Microbe Species (MIC)

General Information of MIC (ID: MC1109)
  MIC Name
Listeria monocytogenes
  Synonym
Bacterium monocytogenes
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Listeriaceae
Genus: Listeria
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Respiratory or Fermentative
  Gram
Positive
  Host Relationship
Pathogen
  Genome Size (bp)
2894716
  No. of Coding Genes
4725
  No. of Non-Coding Genes
107
  No. of Small Non-Coding Genes
107
  No. of Gene Transcripts
4832
  No. of Base Pairs
2776517
  Description
Listeria monocytogenes is the species of pathogenic bacteria that causes the infection listeriosis. It is a facultative anaerobic bacteria, capable of surviving in the presence or absence of oxygen.
  External Links Taxonomy ID 1639
GutMDisorder ID gm0425
Genome Assembly ID ASM719759v1
GOLD Database ID Go0075365
GIMICA ID MIC00771


Full List of Protein(s) Produced by This MIC
     Protein Type: .
           Protein Name: Listeriolysin O Click to Show/Hide
              Detailed Infomation Pro Info click to show the detail information of this protein
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Phosphorylation H3S10 EM Info HeLa cells Cxcl2 Listeria monocytogenes infection [1]
Histone Phosphorylation H3S10 EM Info HeLa cells Dusp4 Listeria monocytogenes infection [1]
Histone Phosphorylation H3S10 EM Info HeLa cells Prkdc Listeria monocytogenes infection [1]
     Protein Type: Microbial secreted proteins
Histone Dephosphorylation H3 EM Info HeLa cells serine 10 Listeria monocytogenes infection [1]
Histone Deacetylation Histone H4 EM Info HeLa cells . Listeria monocytogenes infection [1]
miRNA miR-16 EM Info Epithelial cells . Listeriolysin O infection [4]
miRNA miR-155 EM Info Epithelial cells . Listeriolysin O infection [4]
miRNA miR-146b EM Info Epithelial cells . Listeriolysin O infection [4]
           Protein Name: InIB Click to Show/Hide
              Detailed Infomation Pro Info click to show the detail information of this protein
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Deacetylation H3 EM Info HeLa and CaCO2 cells lysine 18 Listeria monocytogenes infection [2]
           Protein Name: InlB Click to Show/Hide
              Detailed Infomation Pro Info click to show the detail information of this protein
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Deacetylation SIRT2 EM Info . . . [3]
Histone Deacetylation H3 EM Info HeLa cells lysine 18 Listeria innocua infection [2]
Histone Deacetylation H3 EM Info HeLa cells lysine 18 Listeria monocytogenes infection [2]
           Protein Name: LntA Click to Show/Hide
              Detailed Infomation Pro Info click to show the detail information of this protein
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H3K9 EM Info Epithelial cells IFIT3 promoter Listeria monocytogenes infection [5]
Histone Acetylation H3K9 EM Info Epithelial cells IFITM1 promoter Listeria monocytogenes infection [5]

References
1 Histone modifications induced by a family of bacterial toxins Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13467-72. doi: 10.1073/pnas.0702729104. Epub 2007 Aug 3.
2 A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection Science. 2013 Aug 2;341(6145):1238858. doi: 10.1126/science.1238858.
3 Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones Cell Microbiol. 2015 Aug;17(8):1098-107. doi: 10.1111/cmi.12463.
4 microRNA response to Listeria monocytogenes infection in epithelial cells Int J Mol Sci. 2012;13(1):1173-85. doi: 10.3390/ijms13011173. Epub 2012 Jan 20.
5 A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response Science. 2011 Mar 11;331(6022):1319-21. doi: 10.1126/science.1200120. Epub 2011 Jan 20.

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