Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00044)
  Official Symbol
MIR146B
  Official Full Name
microRNA 146b
  Synonym
hsa-mir-146b;MIRN146B
  Molecule Type
miRNA
  Position On Chromosome
chr10(Start:102436512 - End:102436584)
  Strand
+
  ENSG ID
ENSG00000202569 
  Dnmivd Disease
KIRC 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [1]
     Description
Lipopolysaccharide (LPS) has been shown to upregulate miR-146b (4.0-fold) in macrophages.

Protein(s) with this epigenetic modification
  Protein Name: Listeriolysin O
     Detailed Information Pro Info click to show the detail information of this protein [2]
     Description
Listeriolysin O(LLO) has been shown to significantly increased expression of miR-146b in human epithelial (Caco-2) cells.(p value <0.05)

References
1 Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family EMBO J. 2011 May 18;30(10):1977-89. doi: 10.1038/emboj.2011.94. Epub 2011 Apr 5.
2 microRNA response to Listeria monocytogenes infection in epithelial cells Int J Mol Sci. 2012;13(1):1173-85. doi: 10.3390/ijms13011173. Epub 2012 Jan 20.

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