General Information of MIC (ID: MC1085)
  MIC Name
Aggregatibacter actinomycetemcomitans
  Synonym
Actinobacillus actinomycetemcomitans
  Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Pasteurellales
Family: Pasteurellaceae
Genus: Aggregatibacter
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Fermentative
  Gram
Negative
  Host Relationship
Pathogen
  Genome Size (bp)
2367908
  No. of Base Pairs
2367908
  Description
Aggregatibacter actinomycetemcomitans is a gram-negative, facultative anaerobic, nonmotile bacteria that is often found in association with localized aggressive periodontitis, a severe infection of the periodontium.
  External Links Taxonomy ID 714
Genome Assembly ID ASM794v1
GOLD Database ID Go0486805
GIMICA ID MIC00051

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Microbial cell components
           Metabolite Name: Lipopolysaccharide Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial cell components
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
miRNA let-7f EM Info THP-1 cells SOCS4 Cigarette smoke [1]
miRNA let-7f EM Info THP-1 cells TSP-1 Cigarette smoke [1]
miRNA miR-29b EM Info THP-1 cells IFI30 Cigarette smoke [1]
miRNA miR-29b EM Info THP-1 cells IL-6R-alpha Cigarette smoke [1]
miRNA miR-32 EM Info THP-1 cells . Cigarette smoke [1]
miRNA miR-146a EM Info THP-1 cells . Cigarette smoke [1]
miRNA miR-891a EM Info THP-1 cells . Cigarette smoke [1]


References
1 MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages. Innate Immun. 2014 Jul;20(5):540-51. doi: 10.1177/1753425913501914. Epub 2013 Sep 23.

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