Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11156)
  Official Symbol
MIR146A
  Official Full Name
microRNA 146a
  Synonym
MIRN146;MIRN146A;hsa-mir-146;hsa-mir-146a
  Molecule Type
miRNA
  Position On Chromosome
chr5(Start:160485352 - End:160485450)
  Strand
+
  ENSG ID
ENSG00000283733 
  Dnmivd Disease
#N.A 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [1]
     Description
Lipopolysaccharide (LPS) has been shown to upregulate miR-146a (4.0-fold) in macrophages.
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [2]
     Description
Lipopolysaccharide (LPS) has been shown to upregulate miR-146a in human macrophages.

References
1 Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family EMBO J. 2011 May 18;30(10):1977-89. doi: 10.1038/emboj.2011.94. Epub 2011 Apr 5.
2 MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages. Innate Immun. 2014 Jul;20(5):540-51. doi: 10.1177/1753425913501914. Epub 2013 Sep 23.

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