Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10632)
  Official Symbol
MIRLET7F1
  Official Full Name
microRNA let-7f-1
  Synonym
MIRNLET7F1;hsa-let-7f-1
  Molecule Type
miRNA
  Position On Chromosome
chr9(Start:94176347 - End:94176433)
  Strand
+
  ENSG ID
ENSG00000199072 
  Dnmivd Disease
#N.A 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [1]
     Description
Lipopolysaccharide (LPS) has been shown to downregulate let-7f (p < 0.05) in heLa cells.
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [1]
     Description
Lipopolysaccharide (LPS) has been shown to downregulate let-7f (p < 0.05) in macrophages.
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [2]
     Description
Lipopolysaccharide (LPS) has been shown to downregulate let-7f in human macrophages.
  Metabolite Name: Lipopolysaccharide
     Detailed Information Meta Info click to show the detail information of this Metabolite [3]
     Description
Lipopolysaccharide (LPS) has been shown to downregulate let-7f in human macrophages

References
1 Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family EMBO J. 2011 May 18;30(10):1977-89. doi: 10.1038/emboj.2011.94. Epub 2011 Apr 5.
2 Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication. J Virol. 2014 Apr;88(8):4466-79. doi: 10.1128/JVI.03326-13. Epub 2014 Feb 5.
3 MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages. Innate Immun. 2014 Jul;20(5):540-51. doi: 10.1177/1753425913501914. Epub 2013 Sep 23.

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