Details of Microbe Species (MIC)

General Information of MIC (ID: MC0685)
  MIC Name
Brevibacillus agri 5-2
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Paenibacillaceae
Genus: Brevibacillus
  Oxygen Sensitivity
Aerobe
  Microbial Metabolism
Saccharolytic
  Gram
Variable
  Genome Size (bp)
5513716
  No. of Coding Genes
4824
  No. of Non-Coding Genes
137
  No. of Small Non-Coding Genes
137
  No. of Gene Transcripts
5168
  No. of Pseudogenes 207
  Description
Brevibacillus agri 5-2 is a gram-variable and aerobic strain from the genus of Brevibacillus.
  External Links Taxonomy ID 1444307
Genome Assembly ID ASM371088v1
GOLD Database ID Go0081581

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Amino acid (AAs)
           Metabolite Name: Phenylacetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [precursors]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Deacetylation HDAC EM Info . . . [1], [2]
     Molecule Type: Fatty acids
           Metabolite Name: Lactate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
miRNA miR-141-3P EM Info Oral epithelial cells . Autistic spectrum disorder [2], [3]
     Molecule Type: Other metabolites
           Metabolite Name: a-Ketoglutarate (a-Kg) Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [precursors]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Trimethylation H3K27 EM Info Mesenchymal stromal stem cells Nanog promoter Age-related osteoporosis [4], [2]
Histone Trimethylation H3K27 EM Info Mesenchymal stromal stem cells Bmp2 promoter Age-related osteoporosis [2], [3]
Histone Trimethylation H3K27 EM Info Mesenchymal stromal stem cells Bmp4 promoter Age-related osteoporosis [2], [3]
Histone Trimethylation H3K9 EM Info Mesenchymal stromal stem cells Bmp2 promoter Age-related osteoporosis [2], [3]
Histone Trimethylation H3K9 EM Info Mesenchymal stromal stem cells Nanog promoter Age-related osteoporosis [2], [3]


References
1 Potential Associations Among Alteration of Salivary miRNAs, Saliva Microbiome Structure, and Cognitive Impairments in Autistic Children. Int J Mol Sci. 2020 Aug 27;21(17):6203. doi: 10.3390/ijms21176203.
2 The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992.
3 Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations. Nat Commun. 2020 Nov 5;11(1):5596. doi: 10.1038/s41467-020-19360-1.
4 Dietary metabolites derived from gut microbiota: critical modulators of epigenetic changes in mammals. Nutr Rev. 2017 May 1;75(5):374-389. doi: 10.1093/nutrit/nux001.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.