General Information of Metabolite (ID: MT113)
  Meta Name
Flagellin
  Unify Name
Flagellin
  Molecule Type
Microbial components
  Description    Click to Show/Hide the Detailed Description of This Metabolite
Legionella pneumophila-induced phosphorylation of P-Ser10-H3 at the IL-8 promoter depended on flagellin.

The epigenetic modification information of this metabolite
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H3K14 EM Info A549 cells IL-8 promoter . [1]
Histone Phosphorylation H3S10 EM Info A549 cells IL-8 promoter . [1]
Histone Acetylation H4 EM Info A549 cells IL-8 promoter . [1]
Histone Deacetylation HDAC1 EM Info Lung epithelial cells . . [1]
Histone Deacetylation HDAC5 EM Info Lung epithelial cells . . [1]

The microbes that produce this metabolite
      Legionella pneumophila
         Detailed Information MIC Info click to show the detail information of this Microbiota [1]
         Description
Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, gram-negative bacteria of the genus Legionella.

References
1 Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression J Immunol. 2008 Jul 15;181(2):940-7. doi: 10.4049/jimmunol.181.2.940.

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