Details of Protein (Pro)

General Information of Protein (ID: PT033)
  Protein Name
Rv1988
  Unify Protein name
Probable 23S rRNA methyltransferase Erm(37)
  Protein Entry
Q10838 
  Protein Entry name
Q10838_MYCTU
  Protein Length
179AA
  Gene name
erm(37)
  Gene ID
45425967, 885632

The epigenetic modification information of this protein
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA Methylation NOS2 EM Info . promoter Rv1988 infection [1]
DNA Methylation NOX1 EM Info . promoter Rv1988 infection [1]
DNA Methylation NOX4 EM Info . promoter Rv1988 infection [1]
DNA Methylation TRAF3 EM Info . promoter Rv1988 infection [1]
Histone Dimethylation H3 EM Info THP-1 cells arginine 42 Rv1988 infection [2]

The microbes that produce this protein
      Microbiota Name: Mycobacterium tuberculosis
         Detailed Information MIC Info click to show the detail information of this Microbiota [2]
         Description
Mycobacteria tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.
      Microbiota Name: Mycobacterium bovis
         Detailed Information MIC Info click to show the detail information of this Microbiota [2]
         Description
Mycobacteria bovis is a slow-growing aerobic bacteria and the causative agent of tuberculosis in cattle. It is related to Mycobacteria tuberculosis, the bacteria which causes tuberculosis in humans.

References
1 Learning epigenetic regulation from mycobacteria. Microb Cell. 2016 Jan 18;3(2):92-94. doi: 10.15698/mic2016.02.480.
2 Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3 Nat Commun. 2015 Nov 16;6:8922. doi: 10.1038/ncomms9922.

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