Details of Microbe Species (MIC)

General Information of MIC (ID: MC1248)
  MIC Name
Mycobacterium bovis
  Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinomycetia
Order: Actinomycetales
Family: Mycobacteriaceae
Genus: Mycobacterium
  Oxygen Sensitivity
Aerobe
  Microbial Metabolism
Saccharolytic; Respiratory
  Gram
Positive
  Host Relationship
Pathogen
  Description
Mycobacteria bovis is a slow-growing aerobic bacteria and the causative agent of tuberculosis in cattle. It is related to Mycobacteria tuberculosis, the bacteria which causes tuberculosis in humans.


Full List of Protein(s) Produced by This MIC
     Protein Type: Microbial secreted proteins
           Protein Name: Rv1988 Click to Show/Hide
              Detailed Infomation Pro Info click to show the detail information of this protein
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA Methylation TRAF3 EM Info . promoter Rv1988 infection [1]
DNA Methylation NOX4 EM Info . promoter Rv1988 infection [1]
DNA Methylation NOX1 EM Info . promoter Rv1988 infection [1]
DNA Methylation NOS2 EM Info . promoter Rv1988 infection [1]
Histone Dimethylation H3 EM Info THP-1 cells arginine 42 Rv1988 infection [2]

References
1 Learning epigenetic regulation from mycobacteria. Microb Cell. 2016 Jan 18;3(2):92-94. doi: 10.15698/mic2016.02.480.
2 Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3 Nat Commun. 2015 Nov 16;6:8922. doi: 10.1038/ncomms9922.

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