Details of Microbe Species (MIC)

General Information of MIC (ID: MC1042)
  MIC Name
Lactobacilli
  Synonym
Paralactobacillus
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
  Oxygen Sensitivity
Anaerobe
  Microbial Metabolism
Fermentative
  Gram
Positive
  Host Relationship
Probiotic
  Description
Lactobacillus is a genus of gram-positive, aerotolerant anaerobics or microaerophilic, rod-shaped, non-spore-forming bacteria.
  External Links Taxonomy ID 1578

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Butyrate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H3K9 EM Info KGN cells GPR43 . [1], [2]
miRNA miR-92a EM Info Colon cancer cells . Colon cancer [3], [1]


References
1 The microbiota-gut-brain axis: An emerging role for the epigenome. Exp Biol Med (Maywood). 2020 Jan;245(2):138-145. doi: 10.1177/1535370219891690. Epub 2019 Dec 5.
2 Butyrate drives the acetylation of histone H3K9 to activate steroidogenesis through PPAR-gamma and PGC1-alpha pathways in ovarian granulosa cells. FASEB J. 2021 Feb;35(2):e21316. doi: 10.1096/fj.202000444R.
3 Crosstalk between the microbiome and epigenome: messages from bugs. J Biochem. 2018 Feb 1;163(2):105-112. doi: 10.1093/jb/mvx080.

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