Details of Microbe Species (MIC)

General Information of MIC (ID: MC1022)
  MIC Name
Corynebacterium glutamicum
  Synonym
Micrococcus glutamicus
  Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Corynebacteriales
Family: Corynebacteriaceae
Genus: Corynebacterium
  Oxygen Sensitivity
Anaerobe
  Microbial Metabolism
Fermentative
  Gram
Positive
  Genome Size (bp)
3293729
  No. of Base Pairs
3162487
  Description
Corynebacteria glutamicum is a small, non-moving gram-positive soil bacteria. Physically, it is rod shaped with the ends swelled in a shape similar to a club.
  External Links Taxonomy ID 1718
GutMDisorder ID gm0233
GOLD Database ID Go0001353
GIMICA ID MIC00455

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Other metabolites
           Metabolite Name: S-Adenosyl Methionine (SAM) Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [intermediate]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA hypermethylation ASB7 EM Info HT-29 cells Cg20072001 Colorectal carcinoma [1], [2]
DNA hypermethylation MIR636 EM Info HT-29 cells Cg21028463 Colorectal carcinoma [1], [2]
DNA hypermethylation SLC39A6 EM Info HT-29 cells Cg04447424 Colorectal carcinoma [1], [2]
DNA Hypomethylation HAAO EM Info SW480 cells Cg08421126 Colorectal carcinoma [1], [2]
DNA Hypomethylation CRISPLD1 EM Info HT-29 cells Cg15953602 Colorectal carcinoma [1], [2]
DNA Hypomethylation TP53INP1 EM Info HT-29 cells Cg13393036 Colorectal carcinoma [1], [2]
DNA Hypomethylation TSPAN11 EM Info HT-29 cells Cg20372004 Colorectal carcinoma [1], [2]
DNA Hypomethylation DTX1 EM Info HT-29 cells Cg22685245 Colorectal carcinoma [1], [2]
DNA Hypomethylation MYOCD EM Info HT-29 cells Cg20062401 Colorectal carcinoma [1], [2]
DNA Hypomethylation SEZ6L EM Info HT-29 cells Cg09983462 Colorectal carcinoma [1], [2]
DNA Hypomethylation CYP4F22 EM Info HT-29 cells Cg24456663 Colorectal carcinoma [1], [2]
DNA Hypomethylation GATA4 EM Info HT-29 cells Cg14900471 Colorectal carcinoma [1], [2]
DNA Hypomethylation PAK7 EM Info HT-29 cells Cg22457984 Colorectal carcinoma [1], [2]
DNA Hypomethylation SNORA49 EM Info HT-29 cells Cg07588358 Colorectal carcinoma [1], [2]
DNA Hypomethylation TAL1 EM Info SW480 cells Cg11432900 Colorectal carcinoma [1], [2]
DNA Hypomethylation TAL1 EM Info SW480 cells Cg11766986 Colorectal carcinoma [1], [2]
Histone Methylation H3K4 EM Info RAW 264.7 cells TNF-alpha promoter . [3], [2]


References
1 S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression. Cells. 2020 Aug 9;9(8):1864. doi: 10.3390/cells9081864.
2 Progress in the microbial production of S-adenosyl-L-methionine World J Microbiol Biotechnol. 2016 Sep;32(9):153. doi: 10.1007/s11274-016-2102-8. Epub 2016 Jul 27.
3 S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. Hepatology. 2008 May;47(5):1655-66. doi: 10.1002/hep.22231.

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