Details of Microbe Species (MIC)

General Information of MIC (ID: MC1020)
  MIC Name
Kluyveromyces lactis
  Synonym
Candida sphaerica, Kluyveromyces drosophilarum, Kluyveromyces lactis var. drosophilarum
  Lineage Kingdom: Eukaryota
Phylum: Ascomycota
Class: Saccharomycetes
Order: Saccharomycetales
Family: Saccharomycetaceae
Genus: Kluyveromyces
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Respiratory;Fermentative
  Host Relationship
Probiotic
  Description
Kluyveromyces lactis is a facultative anaerobic yeast which has the ability to assimilate lactose and convert it into lactic acid.
  External Links Taxonomy ID 28985

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Other metabolites
           Metabolite Name: S-Adenosyl Methionine (SAM) Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [intermediate]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA hypermethylation ASB7 EM Info HT-29 cells Cg20072001 Colorectal carcinoma [1], [2]
DNA hypermethylation MIR636 EM Info HT-29 cells Cg21028463 Colorectal carcinoma [1], [2]
DNA hypermethylation SLC39A6 EM Info HT-29 cells Cg04447424 Colorectal carcinoma [1], [2]
DNA Hypomethylation HAAO EM Info SW480 cells Cg08421126 Colorectal carcinoma [1], [2]
DNA Hypomethylation CRISPLD1 EM Info HT-29 cells Cg15953602 Colorectal carcinoma [1], [2]
DNA Hypomethylation TP53INP1 EM Info HT-29 cells Cg13393036 Colorectal carcinoma [1], [2]
DNA Hypomethylation TSPAN11 EM Info HT-29 cells Cg20372004 Colorectal carcinoma [1], [2]
DNA Hypomethylation DTX1 EM Info HT-29 cells Cg22685245 Colorectal carcinoma [1], [2]
DNA Hypomethylation MYOCD EM Info HT-29 cells Cg20062401 Colorectal carcinoma [1], [2]
DNA Hypomethylation SEZ6L EM Info HT-29 cells Cg09983462 Colorectal carcinoma [1], [2]
DNA Hypomethylation CYP4F22 EM Info HT-29 cells Cg24456663 Colorectal carcinoma [1], [2]
DNA Hypomethylation GATA4 EM Info HT-29 cells Cg14900471 Colorectal carcinoma [1], [2]
DNA Hypomethylation PAK7 EM Info HT-29 cells Cg22457984 Colorectal carcinoma [1], [2]
DNA Hypomethylation SNORA49 EM Info HT-29 cells Cg07588358 Colorectal carcinoma [1], [2]
DNA Hypomethylation TAL1 EM Info SW480 cells Cg11432900 Colorectal carcinoma [1], [2]
DNA Hypomethylation TAL1 EM Info SW480 cells Cg11766986 Colorectal carcinoma [1], [2]
Histone Methylation H3K4 EM Info RAW 264.7 cells TNF-alpha promoter . [3], [2]


References
1 S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression. Cells. 2020 Aug 9;9(8):1864. doi: 10.3390/cells9081864.
2 Progress in the microbial production of S-adenosyl-L-methionine World J Microbiol Biotechnol. 2016 Sep;32(9):153. doi: 10.1007/s11274-016-2102-8. Epub 2016 Jul 27.
3 S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. Hepatology. 2008 May;47(5):1655-66. doi: 10.1002/hep.22231.

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