Details of Microbe Species (MIC)

General Information of MIC (ID: MC0039)
  MIC Name
Lactobacillus plantarum
  Synonym
Lactobacillus plantari, Lactobacillus arabinosus, Lactobacillus arizonensis
  Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Limosilactobacillus
  Oxygen Sensitivity
Facultative anaerobe
  Microbial Metabolism
Saccharolytic; Respiratory or Fermentative
  Gram
Positive
  Host Relationship
Probiotic
  No. of Coding Genes
3136
  No. of Gene Transcripts
3136
  No. of Base Pairs
3324076
  Description
Lactiplantibacillus plantarum is a species of facultative anaerobic, gram-positive, saccharolytic; fermentative metabolism bacteria.
  External Links Taxonomy ID 1590
GutMDisorder ID gm0393
Genome Assembly ID ASM143685v1
GOLD Database ID Go0005160

Full List of Metabolite(s) Produced by This MIC
     Molecule Type: Fatty acids
           Metabolite Name: Acetate Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [end-products]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
Histone Acetylation H4 EM Info Eosinophil cell Foxo3A promoter Asthma [1], [2]
Histone Acetylation H3K27 EM Info HepG2 cells FASN promoter Hypoxia [3], [4]
Histone Acetylation H3K27 EM Info HepG2 cells LDHA promoter Hypoxia [5], [4]
Histone Acetylation H3K56 EM Info HepG2 cells FASN promoter Hypoxia [5], [4]
Histone Acetylation H3K9 EM Info HepG2 cells ACACA promoter Hypoxia [5], [4]
Histone Acetylation H3K9 EM Info HepG2 cells LDHA promoter Hypoxia [5], [4]
Histone Deacetylation HDAC9 EM Info Eosinophil cell . Asthma [3], [4]
     Molecule Type: Vitamins
           Metabolite Name: Riboflavin (B2) Click to Show/Hide
              Detailed Infomation Meta Info click to show the detail information of this Metabolite
              Metabolic Classification Microbial producted compound [precursors]
Modification Type Molecule EM Info Cell/Tissue Type Modified sites Condition REF
DNA Methylation Zac1 EM Info . . . [5], [4]


References
1 Dietary metabolites derived from gut microbiota: critical modulators of epigenetic changes in mammals. Nutr Rev. 2017 May 1;75(5):374-389. doi: 10.1093/nutrit/nux001.
2 Real-Time Detection of Riboflavin Production by Lactobacillus plantarum Strains and Tracking of Their Gastrointestinal Survival and Functionality in vitro and in vivo Using mCherry Labeling Front Microbiol. 2019 Jul 31;10:1748. doi: 10.3389/fmicb.2019.01748. eCollection 2019.
3 Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.
4 Dynamics and biodiversity of populations of lactic acid bacteria and acetic acid bacteria involved in spontaneous heap fermentation of cocoa beans in Ghana Appl Environ Microbiol. 2007 Mar;73(6):1809-24. doi: 10.1128/AEM.02189-06. Epub 2007 Feb 2.
5 Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016 Jun 30;7:11960. doi: 10.1038/ncomms11960.

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