Details of Metabolite (Meta) | MIAOME

General Information of Metabolite (ID: MT057)
Meta Name		Hydroxyphenylpentanoic acid
Unify Name		Hydroxyphenylpentanoic acid
Molecule Type		Phenolic compounds

The epigenetic modification information of this metabolite
Modification Type																				Molecule																				EM Info								Cell/Tissue Type																		Modified sites																						Condition														REF
DNA Methylation																				DNMT																				EM Info								.																		.																						.														[1], [2]
Histone Deacetylation																				HDAC																				EM Info								.																		.																						.														[1], [2]
Histone Methylation																				HMT																				EM Info								.																		.																						.														[1], [2]

The microbes that produce this metabolite
Bifidobacterium
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1], [2]
Description		Bifidobacteria is a genus of gram-positive, nonmotile, often branched anaerobic bacteria. They are ubiquitous inhabitants of the gastrointestinal tract, vagina and mouth of mammals, including humans.
Subdoligranulum
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1], [3]
Description		Subdoligranulum is a genus of gram-negative, strictly anaerobic bacteria from the family Oscillospiraceae.
Clostridium difficile
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1], [3]
Description		Clostridioides difficile is a species of gram-positive, anaerobic bacteria from the genus Clostridioides.
Lactobacillus
Detailed Information		MIC Info click to show the detail information of this Microbiota					[4], [1]
Description		Lactobacillus is a genus of gram-positive, facultative anaerobic or microaerophilic, rod-shaped, non-spore-forming bacteria. They are a major part of the lactic acid bacteria group. In humans, they constitute a significant component of the microbiota at a number of body sites, such as the digestive system, urinary system, and genital system.

References
1	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2	Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.
3	Lysine benzoylation is a histone mark regulated by SIRT2. Nat Commun. 2018 Aug 28;9(1):3374. doi: 10.1038/s41467-018-05567-w.
4	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.

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