Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00061)
  Official Symbol
HIST1H2BC
  Official Full Name
histone cluster 1, H2bc
  Synonym
H2B.1;H2B.1A;H2B.h;H2B/a;H2B/g;H2B/h;H2B/k;H2B/l;H2BFA;H2BFG;H2BFH;H2BFK;H2BFL;HIST1H2BC;HIST1H2BE;HIST1H2BF;HIST1H2BI;dJ221C16.3;dJ221C16.8
  Molecule Type
Protein coding
  Position On Chromosome
chr6(Start:26114873 - End:26123926)
  Strand
-
  Uniprot Entry
P62807 
  ENSG ID
ENSG00000180596 
  Dnmivd Disease
LUAD 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Benzoate
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Benzoate has been shown to enhance the H2BK20 benzoylation levels in HepG2 cells.
  Metabolite Name: Benzoate
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Benzoate has been shown to enhance the H2BK16 benzoylation levels in HepG2 cells.
  Metabolite Name: Benzoate
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Benzoate has been shown to enhance the H2BK5 benzoylation levels in HepG2 cells.
  Metabolite Name: Benzoate
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Benzoate has been shown to enhance the H2BK11 benzoylation levels in HepG2 cells.

Protein(s) with this epigenetic modification
  Protein Name: NuE
     Detailed Information Pro Info click to show the detail information of this protein [3]
     Description
NuE could methylates H2B.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.
3 Histone methylation by NUE, a novel nuclear effector of the intracellular pathogen Chlamydia trachomatis PLoS Pathog. 2010 Jul 15;6(7):e1000995. doi: 10.1371/journal.ppat.1000995.

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