Drug Information

Drug General Information
Drug ID
D0XX9G
Former ID
DNC014559
Drug Name
(3-Amino-propyl)-hydroxymethyl-phosphinic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533678]
Formula
C4H12NO3P
Canonical SMILES
C(CN)CP(=O)(CO)O
InChI
1S/C4H12NO3P/c5-2-1-3-9(7,8)4-6/h6H,1-5H2,(H,7,8)
InChIKey
ZAQYGKUMUQDMEV-UHFFFAOYSA-N
PubChem Compound ID
3574432
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [533678]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 533678J Med Chem. 1995 Aug 18;38(17):3297-312.Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.
Ref 533678J Med Chem. 1995 Aug 18;38(17):3297-312.Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.

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