Drug Information

Drug General Information
Drug ID
D0H2LT
Former ID
DNC014692
Drug Name
4-Amino-3-(2-chloro-phenyl)-butyric acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528071]
Formula
C10H12ClNO2
Canonical SMILES
C1=CC=C(C(=C1)C(CC(=O)O)CN)Cl
InChI
1S/C10H12ClNO2/c11-9-4-2-1-3-8(9)7(6-12)5-10(13)14/h1-4,7H,5-6,12H2,(H,13,14)
InChIKey
RNSIJRUPQJHCBR-UHFFFAOYSA-N
PubChem Compound ID
21950279
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [528071]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 528071J Med Chem. 1991 Aug;34(8):2557-60.3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.
Ref 528071J Med Chem. 1991 Aug;34(8):2557-60.3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.

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