Drug Information

Drug General Information
Drug ID
D0W6RV
Former ID
DIB021209
Drug Name
WAY-163909
Synonyms
WAY163909
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539440]
Formula
C14H18N2
InChI
InChI=1S/C14H18N2/c1-3-10-9-15-7-8-16-13-6-2-4-11(13)12(5-1)14(10)16/h1,3,5,11,13,15H,2,4,6-9H2/t11-,13-/m1/s1
InChIKey
XOSKJKGKWRIMGV-DGCLKSJQSA-N
PubChem Compound ID
10130594
PubChem Substance ID
15121288, 15172007, 22533413, 39969024, 50074643, 77430825, 124974705, 134224525, 135651322, 135653874, 143236861, 163394691, 163842996, 172919868, 223556767, 230289428, 246317197, 250212617, 252492709
Target and Pathway
Target(s) 5-hydroxytryptamine 2C receptor Target Info Agonist [527428]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 539440(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 229).
Ref 527428WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity. J Pharmacol Exp Ther. 2005 May;313(2):862-9. Epub 2005 Feb 10.

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