Drug Information

Drug General Information
Drug ID
D0V4FZ
Former ID
DIB020954
Drug Name
SKF-75670
Drug Type
Small molecular drug
Indication Discovery agent Investigative [543310]
Formula
C17H19NO2
InChI
InChI=1S/C17H19NO2/c1-18-8-7-13-9-16(19)17(20)10-14(13)15(11-18)12-5-3-2-4-6-12/h2-6,9-10,15,19-20H,7-8,11H2,1H3
InChIKey
LIHCKGZEDBNUJG-UHFFFAOYSA-N
PubChem Compound ID
173871
PubChem Substance ID
33498127, 47275550, 50111237, 52627093, 54233418, 85209306, 90341826, 113474512, 124750225, 124881428, 128493220, 131342560, 135651049, 140154768, 141979010, 163636966, 236871138, 242105057
Target and Pathway
Target(s) Dopamine D1 receptor Target Info Agonist [530363]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Morphine addiction
Alcoholism
PANTHER Pathway Dopamine receptor mediated signaling pathway
PathWhiz Pathway Dopamine Activation of Neurological Reward System
Reactome Dopamine receptors
G alpha (s) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
References
Ref 543310(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 936).
Ref 530363Dopamine receptor agonists: selectivity and dopamine D1 receptor efficacy. Eur J Pharmacol. 1990 Jun 12;188(6):335-47.

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