Drug Information

Drug General Information
Drug ID
D0U9XC
Former ID
DNC014616
Drug Name
(3-Amino-phenyl)-phosphonic acid diphenyl ester
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533549]
Formula
C18H16NO3P
Canonical SMILES
C1=CC=C(C=C1)OP(=O)(C2=CC=CC(=C2)N)OC3=CC=CC=C3
InChI
1S/C18H16NO3P/c19-15-8-7-13-18(14-15)23(20,21-16-9-3-1-4-10-16)22-17-11-5-2-6-12-17/h1-14H,19H2
InChIKey
CJCPJYQCUVSSBA-UHFFFAOYSA-N
PubChem Compound ID
44373237
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [533549]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 533549J Med Chem. 1984 May;27(5):654-9.Phosphorus analogues of gamma-aminobutyric acid, a new class of anticonvulsants.
Ref 533549J Med Chem. 1984 May;27(5):654-9.Phosphorus analogues of gamma-aminobutyric acid, a new class of anticonvulsants.

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