Drug Information

Drug General Information
Drug ID
D0U8RZ
Former ID
DNC004866
Drug Name
2-[1-(2-Chloro-phenyl)-1H-pyrrol-2-yl]-ethylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527627]
Formula
C12H13ClN2
Canonical SMILES
C1=CC=C(C(=C1)N2C=CC=C2CCN)Cl
InChI
1S/C12H13ClN2/c13-11-5-1-2-6-12(11)15-9-3-4-10(15)7-8-14/h1-6,9H,7-8,14H2
InChIKey
QDZRUXBRYDSOHU-UHFFFAOYSA-N
PubChem Compound ID
44388886
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Inhibitor [527627]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 527627Bioorg Med Chem Lett. 2005 Aug 15;15(16):3753-7.Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.
Ref 527627Bioorg Med Chem Lett. 2005 Aug 15;15(16):3753-7.Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.

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