Drug Information

Drug General Information
Drug ID
D0S9XO
Former ID
DIB020328
Drug Name
mercaptoacrylate inhibitor of calpain 1
Drug Type
Small molecular drug
Indication Discovery agent Investigative [543197]
Formula
C11H8BrNO2S
InChI
InChI=1S/C11H8BrNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-
InChIKey
RLEKFRNXGFHPHZ-KMKOMSMNSA-N
PubChem Compound ID
90668184
PubChem Substance ID
242616608, 252166771
Target and Pathway
Target(s) Calpain Target Info Inhibitor [543595]
KEGG Pathway Protein processing in endoplasmic reticulum
Apoptosis
Alzheimer's disease
Reactome Degradation of the extracellular matrix
WikiPathways Focal Adhesion
Integrated Pancreatic Cancer Pathway
Alzheimers Disease
Integrin-mediated Cell Adhesion
References
Ref 543197(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8570).
Ref 543595(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2336).

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