Drug Information

Drug General Information
Drug ID
D0OW6Q
Former ID
DNC006902
Drug Name
2,3'-diamino-3,4,4',5-tetramethoxy-(Z)-stillbene
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528474]
Formula
C18H22N2O4
Canonical SMILES
COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2N)OC)OC)OC)N
InChI
1S/C18H22N2O4/c1-21-14-8-6-11(9-13(14)19)5-7-12-10-15(22-2)17(23-3)18(24-4)16(12)20/h5-10H,19-20H2,1-4H3/b7-5-
InChIKey
ONFPNROXTUMLBU-ALCCZGGFSA-N
PubChem Compound ID
16090839
Target and Pathway
Target(s) Tubulin beta-2 chain Target Info Inhibitor [528474]
Tubulin beta Target Info Inhibitor [528474]
KEGG Pathway Phagosome
Gap junction
Pathogenic Escherichia coli infection
NetPath Pathway FSH Signaling Pathway
TCR Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Cytoskeletal regulation by Rho GTPase
Huntington disease
Reactome Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization?from the centrosome
Anchoring of the basal body to the plasma membrane
WikiPathways Parkin-Ubiquitin Proteasomal System pathway
Pathogenic Escherichia coli infection
Mitotic G2-G2/M phases
References
Ref 528474J Med Chem. 2006 Oct 19;49(21):6412-5.2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
Ref 528474J Med Chem. 2006 Oct 19;49(21):6412-5.2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.

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