Drug Information

Drug General Information
Drug ID
D0OQ4H
Former ID
DIB014129
Drug Name
A-69024
Drug Type
Small molecular drug
Indication Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] Terminated [545268]
Company
Abbott Laboratories
Formula
C20H24BrNO4
Canonical SMILES
c12C(N(CCc1cc(c(c2)O)OC)C)Cc1c(cc(c(c1)OC)OC)Br
CAS Number
CAS 58939-37-0
PubChem Compound ID
173657
Target and Pathway
Target(s) Dopamine D1 receptor Target Info Modulator [526304]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Morphine addiction
Alcoholism
PANTHER Pathway Dopamine receptor mediated signaling pathway
PathWhiz Pathway Dopamine Activation of Neurological Reward System
Reactome Dopamine receptors
G alpha (s) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
References
Ref 545268Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002637)
Ref 526304(+)-[76Br]A-69024: a non-benzazepine radioligand for studies of dopamine D1 receptors using PET. Nucl Med Biol. 2002 Apr;29(3):295-302.

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