Drug Information

Drug General Information
Drug ID
D0N4WZ
Former ID
DNC014550
Drug Name
CGP-36216
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551250]
Formula
C5H14NO2P
Canonical SMILES
CCP(=O)(CCCN)O
InChI
1S/C5H14NO2P/c1-2-9(7,8)5-3-4-6/h2-6H2,1H3,(H,7,8)
InChIKey
RWCIPYZWXPUGRM-UHFFFAOYSA-N
PubChem Compound ID
9898878
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [551250]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 551250Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity, Bioorg. Med. Chem. Lett. 3(4):515-518 (1993).
Ref 551250Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity, Bioorg. Med. Chem. Lett. 3(4):515-518 (1993).

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