Drug Information

Drug General Information
Drug ID
D0I0ML
Former ID
DNC007747
Drug Name
2-(2'-methyl-biphenyl-3-yl)-ethylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528780]
Formula
C15H17N
Canonical SMILES
CC1=CC=CC=C1C2=CC(=CC=C2)CCN
InChI
1S/C15H17N/c1-12-5-2-3-8-15(12)14-7-4-6-13(11-14)9-10-16/h2-8,11H,9-10,16H2,1H3
InChIKey
KQRAKUVQYREATE-UHFFFAOYSA-N
PubChem Compound ID
35985234
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [528780]
5-hydroxytryptamine 7 receptor Target Info Inhibitor [528780]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04014:Ras signaling pathway
Calcium signaling pathway
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (i) signalling eventsR-HSA-390666:Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP734:Serotonin Receptor 4/6/7 and NR3C Signaling
GPCR downstream signaling
GPCRs, Other
References
Ref 528780Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
Ref 528780Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

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