Drug Information

Drug General Information
Drug ID
D0B9TN
Former ID
DNC010459
Drug Name
2-(2-Bromophenylthio)-N,N-dimethylethanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530699]
Formula
C10H14BrNS
Canonical SMILES
CN(C)CCSC1=CC=CC=C1Br
InChI
1S/C10H14BrNS/c1-12(2)7-8-13-10-6-4-3-5-9(10)11/h3-6H,7-8H2,1-2H3
InChIKey
WXAWOWHEHSIUMN-UHFFFAOYSA-N
PubChem Compound ID
46233353
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Inhibitor [530699]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 530699Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.
Ref 530699Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.

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