Drug Information

Drug General Information
Drug ID
D09YCW
Former ID
DNC014694
Drug Name
4-Amino-3-(5-methyl-thiophen-2-yl)-butyric acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528071]
Formula
C9H13NO2S
Canonical SMILES
CC1=CC=C(S1)C(CC(=O)O)CN
InChI
1S/C9H13NO2S/c1-6-2-3-8(13-6)7(5-10)4-9(11)12/h2-3,7H,4-5,10H2,1H3,(H,11,12)
InChIKey
RPNWEWXYTFWDTR-UHFFFAOYSA-N
PubChem Compound ID
125916
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [528071]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 528071J Med Chem. 1991 Aug;34(8):2557-60.3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.
Ref 528071J Med Chem. 1991 Aug;34(8):2557-60.3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.

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