Drug Information

Drug General Information
Drug ID
D09WJO
Former ID
DNC014697
Drug Name
4-Amino-3-thiophen-2-yl-butyric acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528071]
Formula
C8H11NO2S
Canonical SMILES
C1=CSC(=C1)C(CC(=O)O)CN
InChI
1S/C8H11NO2S/c9-5-6(4-8(10)11)7-2-1-3-12-7/h1-3,6H,4-5,9H2,(H,10,11)
InChIKey
QDVRXIPQICAUFK-UHFFFAOYSA-N
PubChem Compound ID
131689
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [528071]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 528071J Med Chem. 1991 Aug;34(8):2557-60.3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.
Ref 528071J Med Chem. 1991 Aug;34(8):2557-60.3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.

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