Drug Information

Drug General Information
Drug ID
D03OUU
Former ID
DNC012630
Drug Name
6-(2-Amino-ethyl)-biphenyl-2,3,4'-triol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533481]
Formula
C14H15NO3
Canonical SMILES
C1=CC(=CC=C1C2=C(C=CC(=C2O)O)CCN)O
InChI
1S/C14H15NO3/c15-8-7-10-3-6-12(17)14(18)13(10)9-1-4-11(16)5-2-9/h1-6,16-18H,7-8,15H2
InChIKey
AHHHSPLFRASFOU-UHFFFAOYSA-N
PubChem Compound ID
44299852
Target and Pathway
Target(s) Dopamine D1 receptor Target Info Inhibitor [533481]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Morphine addiction
Alcoholism
PANTHER Pathway Dopamine receptor mediated signaling pathway
PathWhiz Pathway Dopamine Activation of Neurological Reward System
Reactome Dopamine receptors
G alpha (s) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
References
Ref 533481J Med Chem. 1986 Oct;29(10):1904-12.Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.
Ref 533481J Med Chem. 1986 Oct;29(10):1904-12.Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.

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