Drug Information

Drug General Information
Drug ID
D02ACL
Former ID
DIB018958
Drug Name
benzamil
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467490]
Formula
C13H14ClN7O
InChI
InChI=1S/C13H14ClN7O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22)
InChIKey
KXDROGADUISDGY-UHFFFAOYSA-N
PubChem Compound ID
108107
PubChem Substance ID
586340, 621649, 4997149, 11110839, 11110840, 11120241, 11120729, 11121217, 11121645, 11122125, 11336176, 11361415, 11362714, 11365276, 11367838, 11370699, 11370700, 11373064, 11373439, 11376000, 11462387, 11466685, 11467805, 11486350, 11491638, 15248269, 26755660, 26755661, 44437002, 47870415, 47870416, 48019678, 48019679, 48095241, 48244091, 48318723, 48319195, 48319196, 48394633, 49698609, 50068048, 50110974, 50110975, 50686741, 53849316, 57338445, 85787710, 85787961, 90341795, 92309106
Target and Pathway
Target(s) ENaCalphabetagamma Target Info Blocker (channel blocker) [543954]
TRPP2 Target Info Blocker (channel blocker) [543860]
Acid-sensing ion channel ASIC3 Target Info Blocker (channel blocker) [543913]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome Stimuli-sensing channels
WikiPathways Iron uptake and transport
References
Ref 467490(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4145).
Ref 543860(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 505).
Ref 543913(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 684).
Ref 543954(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 742).

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