Drug Information

Drug General Information
Drug ID
D0C7LS
Former ID
DNC002864
Drug Name
Guanosine-5'-Diphosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539540]
Formula
C10H15N5O11P2
InChI
InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKey
QGWNDRXFNXRZMB-UUOKFMHZSA-N
CAS Number
CAS 146-91-8
PubChem Compound ID
8977
PubChem Substance ID
3337, 583751, 584111, 584136, 584228, 584348, 584712, 584811, 585261, 585344, 818958, 819234, 819879, 820012, 820014, 820264, 820293, 820381, 820471, 820972, 821371, 821373, 822400, 822404, 822538, 822865, 823431, 823622, 823761, 823857, 824048, 824692, 825088, 825257, 825639, 825828, 825859, 826565, 826676, 826786, 827085, 827286, 827287, 827320, 828342, 828602, 828700, 829000, 829370, 830432
Target and Pathway
Target(s) Elongation factor 2 Target Info Inhibitor [551393]
Elongation factor G Target Info Inhibitor [551393]
Protein-glutamine gamma-glutamyltransferase Target Info Inhibitor [551393]
Adenylosuccinate synthetase Target Info Inhibitor [551393]
Elongation factor 1-alpha Target Info Inhibitor [551393]
Elongation factor 1-alpha 1 Target Info Inhibitor [551393]
YihA Target Info Inhibitor [551393]
Celldivision protein FtsZ Target Info Inhibitor [551393]
Ras-related protein Rab-9A Target Info Inhibitor [551393]
KEGG Pathway Huntington's diseasehsa05162:Measles
Pathway Interaction Database Beta1 integrin cell surface interactions
Thromboxane A2 receptor signaling
Alpha9 beta1 integrin signaling events
References
Ref 539540(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2410).
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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