Target Information

Target General Infomation
Target ID
T88125
Former ID
TTDR00932
Target Name
YihA
Gene Name
engB
Synonyms
Probable GTP-binding protein engB; engB
Target Type
Research
Function
Necessary for normal cell division and for the maintenance of normal septation. Depletion of this protein leads to a severe reduction in growth rate and to extensive filamentation, with a block beyond the stage of segregation. Essential for bacteria survivial.
UniProt ID
P0A6P7
Sequence
MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPG
RTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRH
PLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVETFSS
LKKQGVDKLRQKLDTWFSEMQPVEETQDGE
Inhibitor Guanosine-5'-Diphosphate Drug Info [551393]
Guanosine-5'-Triphosphate Drug Info [551393]
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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