Drug Information

Drug General Information
Drug ID
D0TV9K
Former ID
DIB015040
Drug Name
Propiverine
Drug Type
Small molecular drug
Indication Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32] Approved [551871]
Formula
C23H30ClNO3
Canonical SMILES
C(=O)(C(c1ccccc1)(c1ccccc1)OCCC)OC1CCN(CC1)C
CAS Number
CAS 60569-19-9
PubChem Compound ID
441412
Target and Pathway
Target(s) Acetylcholine receptor Target Info Antagonist [525517], [551871]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Muscarinic acetylcholine receptors
Acetylcholine regulates insulin secretion
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 525517Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland. Life Sci. 1999;64(25):2351-8.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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