Drug Information

Drug General Information
Drug ID
D0IJ2H
Former ID
DIB001212
Drug Name
FK-584
Drug Type
Small molecular drug
Indication Central and peripheral nervous diseases [ICD10:G96.9] Discontinued in Phase 2 [546161]
Company
Fujisawa Pharmaceutical Co Ltd
Formula
C17H18ClN
Canonical SMILES
C1(C=C[C@H](C1)NC(C)(C)C)(c1ccccc1)c1ccccc1
CAS Number
CAS 138951-54-9
PubChem Compound ID
171539
Target and Pathway
Target(s) Acetylcholine receptor Target Info Modulator [550892]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Muscarinic acetylcholine receptors
Acetylcholine regulates insulin secretion
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 546161Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006686)
Ref 550892US patent application no. 2005,0261,328, Pharmaceutical composition comprising beta-3-adrenoceptor-agonists and antimuscarinic agents.

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