Drug Information

Drug General Information
Drug ID
D07OQF
Former ID
DIB019515
Drug Name
compound 4d
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525780], [533065]
Formula
C17H10BrClO4
InChI
InChI=1S/C17H10BrClO4/c18-9-10-4-5-15-11(6-10)7-14(17(21)23-15)16(20)22-13-3-1-2-12(19)8-13/h1-8H,9H2
InChIKey
RNWNTBMGGUARMR-UHFFFAOYSA-N
PubChem Compound ID
90170031
PubChem Substance ID
240666465, 252166691
Target and Pathway
Target(s) Kallikrein 7 Target Info Inhibitor [533065]
kallikrein-related peptidase 5 Target Info Inhibitor [533065]
Suppressor of tumorigenicity 14 Target Info Inhibitor [533065]
kallikrein-related peptidase 14 Target Info Inhibitor [533065]
KEGG Pathway MicroRNAs in cancer
NetPath Pathway TCR Signaling Pathway
Reactome Degradation of the extracellular matrix
WikiPathways Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
References
Ref 525780Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome. Nat Genet. 2000 Jun;25(2):141-2.
Ref 533065Toward the first class of suicide inhibitors of kallikreins involved in skin diseases. J Med Chem. 2015 Jan 22;58(2):598-612.
Ref 533065Toward the first class of suicide inhibitors of kallikreins involved in skin diseases. J Med Chem. 2015 Jan 22;58(2):598-612.

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